About   Help   FAQ
Slc39a3
Gene Detail
Symbol

Name
ID
Slc39a3
solute carrier family 39 (zinc transporter), member 3
MGI:2147269
Synonyms
MGC:7461, zip3
Feature Type
protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:81028538-81037426 bp, - strand
From VEGA annotation of GRCm38

  8889 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:44230  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: SLC39A3
Gene Tree: Slc39a3

Human
homologs
SLC39A3, solute carrier family 39 (zinc transporter), member 3
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 29985
neXtProt AC: NX_Q9BRY0

Human Synonyms: ZIP3, ZIP-3

Human Chr (Location): 19p13.3; chr19:2732524-2740076 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice stressed with a zinc-deficient diet during pregnancy or at weaning exhibit a subtle increase in the sensitivity to abnormal morphogenesis of the embryo and to depletion of thymic pre-T cells, respectively.
 
Interactions
Slc39a3 interacts with 223 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (211)    Tissues (127)    Images (37)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 194
In situ reporter (knock in) 11
Northern blot 6
cDNA source data(54)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc39a3 ; ZFIN slc39a3    NEW 
Molecular
reagents
All nucleic(55) cDNA(55)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000030300 (Evidence)
Ensembl Gene Model ENSMUSG00000046822 (Evidence)
Entrez Gene 106947 (Evidence)
UniGene 5353
DFCI TC1577373
DoTS DT.529201
NIA Mouse Gene Index U032031
Consensus CDS Project CCDS24041.1
International Mouse Phenotyping Consortium Status Slc39a3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030300 VEGA Gene Model | MGI Sequence Detail 8889 C57BL/6J ±  kb
transcript OTTMUST00000075012 VEGA | MGI Sequence Detail 3796 Not Applicable 
polypeptide OTTMUSP00000039253 VEGA | MGI Sequence Detail 317 Not Applicable 

For the selected sequences
All sequences(52) RefSeq(14) UniProt(1)
Polymorphisms
SNPs within 2kb(37 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003689 Zinc/iron permease
Protein Ontology PR:000015130 zinc transporter ZIP3
References
(Earliest) J:87178 Dufner-Beattie J, et al., Structure, function, and regulation of a subfamily of mouse zinc transporter genes. J Biol Chem. 2003 Dec 12;278(50):50142-50
(Latest) J:167854 Qian J, et al., Knockout of Zn transporters Zip-1 and Zip-3 attenuates seizure-induced CA1 neurodegeneration. J Neurosci. 2011 Jan 5;31(1):97-104
All references(36)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/21/2015
MGI 5.22
The Jackson Laboratory