About   Help   FAQ
Take the Alliance for Genomic Resources User Survey
Dhx57 Gene Detail
Summary
  • Symbol
    Dhx57
  • Name
    DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147067
    NCBI Gene: 106794
  • Gene Overview
    MyGene.info: DHX57
Location & Maps
more
  • Sequence Map
    Chr17:80238304-80290476 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      52173 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 50.63 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DHX57, DEAH-box helicase 57
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DHX57, DEAH-box helicase 57
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DDX57
  • Links
    NCBI Gene ID: 90957
    neXtProt AC: NX_Q6P158

  • Chr Location
    2p22.1; chr2:38797729-38875883 (-)  GRCh38.p2
  • HomoloGene
    Vertebrate Homology Class 56267
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: DHX57
  • Gene Tree
    Dhx57
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    40
  • Tissues
    27
  • cDNA Data
    97
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 106794 NCBI Gene Model | MGI Sequence Detail 52173 C57BL/6J ±  kb
transcript NM_001163759 RefSeq | MGI Sequence Detail 5094 C57BL/6  
polypeptide Q6P5D3 UniProt | EBI | MGI Sequence Detail 1388 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    328 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 97
    cDNA 97

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
09/13/2016
MGI 6.05 		The Jackson Laboratory