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Stap2 Gene Detail
Summary
  • Symbol
    Stap2
  • Name
    signal transducing adaptor family member 2
  • Synonyms
    STAP-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147039
    NCBI Gene: 106766
  • Gene Overview
    MyGene.info: STAP2
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:55997081-56005570 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 29.10 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    39 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147039
protein coding gene Chr17:55997074-56008131 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023906
protein coding gene Chr17:57617878-57626640 (-)
A/J MGP_AJ_G0023866
protein coding gene Chr17:56068272-56076596 (-)
AKR/J MGP_AKRJ_G0023835
protein coding gene Chr17:56752611-56761560 (-)
BALB/cJ MGP_BALBcJ_G0023867
protein coding gene Chr17:55903251-55911941 (-)
C3H/HeJ MGP_C3HHeJ_G0023630
protein coding gene Chr17:57459658-57469424 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024311
protein coding gene Chr17:59902178-59910701 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021758
protein coding gene Chr17:52586245-52594896 (-)
CAST/EiJ MGP_CASTEiJ_G0023113
protein coding gene Chr17:57763902-57772156 (-)
CBA/J MGP_CBAJ_G0023607
protein coding gene Chr17:62199353-62213609 (-)
DBA/2J MGP_DBA2J_G0023735
protein coding gene Chr17:54802550-54810977 (-)
FVB/NJ MGP_FVBNJ_G0023701
protein coding gene Chr17:54317864-54326604 (-)
LP/J MGP_LPJ_G0023815
protein coding gene Chr17:58342467-58352380 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023728
protein coding gene Chr17:61768276-61778235 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024356
protein coding gene Chr17:57127295-57137554 (-)
PWK/PhJ MGP_PWKPhJ_G0022858
protein coding gene Chr17:54144190-54154477 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022670
protein coding gene Chr17:53890354-53904116 (-)
WSB/EiJ MGP_WSBEiJ_G0023177
protein coding gene Chr17:57738657-57749716 (-)



Homology
more
  • Human Ortholog
    STAP2, signal transducing adaptor family member 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    STAP2, signal transducing adaptor family member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BKS
  • Links
    NCBI Gene ID: 55620
    neXtProt AC: NX_Q9UGK3
    UniProt: Q9UGK3

  • Chr Location
    19p13.3; chr19:4324043-4338877 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Mice homozygous for a knock-out allele are viable and fertile and display no apparent abnormalities in most organs at the gross and histological level.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038781 Ensembl Gene Model | MGI Sequence Detail 8490 C57BL/6J ±  kb
transcript ENSMUST00000043785 Ensembl | MGI Sequence Detail 1509 Not Applicable  
polypeptide ENSMUSP00000038130 Ensembl | MGI Sequence Detail 411 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 66
    cDNA 66

    Microarray probesets 5
References
more
  • Summaries
    All 32
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:82584 Minoguchi M, et al., STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif. J Biol Chem. 2003 Mar 28;278(13):11182-9
  • Latest
    J:210230 Sekine Y, et al., Signal-transducing adaptor protein-2 controls the IgE-mediated, mast cell-mediated anaphylactic responses. J Immunol. 2014 Apr 15;192(8):3488-95

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory