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Catsperd Gene Detail
Summary
  • Symbol
    Catsperd
  • Name
    catsper channel auxiliary subunit delta
  • Synonyms
    4921529N20Rik, 4933402B14Rik, Gm6095, Tmem146
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147030
    NCBI Gene: 106757
Location & Maps
more
  • Genetic Map
    Chromosome 17, 29.43 cM
  • Mapping Data
    3 experiments
Homology
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  • Human Ortholog
    CATSPERD, cation channel sperm associated auxiliary subunit delta
  • Vertebrate Orthologs
    6
  • Human Ortholog
    CATSPERD, cation channel sperm associated auxiliary subunit delta
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TMEM146
  • Links
    NCBI Gene ID: 257062
    neXtProt AC: NX_Q86XM0

  • Chr Location
    19p13.3; chr19:5720401-5778734 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Targeted
    1
  • Incidental Mutations
    APF
Mice homozygous for a deletion in this gene display male infertility. Hyperactivity of sperm fails to develop under capacitating conditions.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040828 Ensembl Gene Model | MGI Sequence Detail 36314 C57BL/6J ±  kb
transcript ENSMUST00000112979 Ensembl | MGI Sequence Detail 2565 Not Applicable  
polypeptide ENSMUSP00000108603 Ensembl | MGI Sequence Detail 805 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    143 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000031295 cation channel sperm-associated protein subunit delta
  • InterPro Domains
    IPR028751 Cation channel sperm-associated protein subunit delta
Molecular
Reagents
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  • All nucleic 10
    Genomic 1
    cDNA 9

    Microarray probesets 4
Other
Accession IDs
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MGI:1918194, MGI:3779551
References
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  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:214399 Chung JJ, et al., Structurally distinct Ca(2+) signaling domains of sperm flagella orchestrate tyrosine phosphorylation and motility. Cell. 2014 May 8;157(4):808-22

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory