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Gnptg
Gene Detail
Symbol

Name
ID
Gnptg
N-acetylglucosamine-1-phosphotransferase, gamma subunit
MGI:2147006
Feature Type
protein coding gene
Genetic Map
Chromosome 17
12.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr17:25234317-25240170 bp, - strand
From NCBI annotation of GRCm38

  5854 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:13047  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GNPTG
Protein SuperFamily: N-acetylglucosamine-1-phosphotransferase, gamma subunit
Gene Tree: Gnptg

Human
homologs
GNPTG, N-acetylglucosamine-1-phosphate transferase, gamma subunit
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 84572
neXtProt AC: NX_Q9UJJ9

Human Synonyms: C16orf27, GNPTAG, LP2537, RJD9

Human Chr (Location): 16p13.3; chr16:1351899-1363351 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human GNPTG

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Radiation induced(2) Targeted(3)
Genomic Mutations involving Gnptg (2)
 
Mice homozygous for a knock-out allele show a partial loss of lysosomal enzyme phosphorylation.
 
Interactions
Gnptg interacts with 175 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Expression
Literature Summary: (1 records)
Data Summary: Results (16)    Tissues (14)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 2
RT-PCR 14
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase gnptg    NEW 
Molecular
reagents
All nucleic(6) cDNA(5) Primer pair(1)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000035521 (Evidence)
Entrez Gene 214505 (Evidence)
NIA Mouse Gene Index U037550
Consensus CDS Project CCDS28511.1
International Mouse Phenotyping Consortium Status Gnptg
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 214505 NCBI Gene Model | MGI Sequence Detail 5854 C57BL/6J ±  kb
transcript NM_172529 RefSeq | MGI Sequence Detail 1234 C57BL/6 
polypeptide Q6S5C2 UniProt | EBI | MGI Sequence Detail 307 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(75 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009011 Mannose-6-phosphate receptor binding domain
Protein Ontology PR:000008126 N-acetylglucosamine-1-phosphotransferase subunit gamma
Graphical View of Protein Domain Structure
References
(Earliest) J:96976 Sun Q, et al., Overexpression of mouse GlcNAc-1-phosphotransferase-gamma subunit in cells induced an I-cell-like phenotype of mucolipidosis. Gene. 2005 Feb 28;347(1):55-64
(Latest) J:206913 Encarnacao M, et al., Post-translational modifications of the gamma-subunit affect intracellular trafficking and complex assembly of GlcNAc-1-phosphotransferase. J Biol Chem. 2011 Feb 18;286(7):5311-8
All references(24)
Other
accession IDs
MGI:2147005

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory