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Trip10
Gene Detail
 Symbol
Name
ID
Trip10
thyroid hormone receptor interactor 10
MGI:2146901
Synonyms Cip4
Feature Type protein coding gene
Genetic Map
Chromosome 17
29.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:57249451-57263697 bp, + strand
From NCBI annotation of GRCm38

  14247 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:99728  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Trip10

Human
homologs
Human Homolog TRIP10, thyroid hormone receptor interactor 10
NCBI Gene ID 9322
neXtProt AC  NX_Q15642
Human Synonyms  CIP4, HSTP, STOT, STP, TRIP-10
Human Chr (Location)  19p13.3; chr19:6739682-6751526 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(6) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit increased insulin-stimulated glucose uptake in adipocytes and decreased circulating glucose levels. Mice homozygous for another knock-out allele exhibit impaired integrin-dependent T-cell trafficking.
 
Interactions
Trip10 interacts with 146 markers (Mir7-1, Mir7b, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process endocytosis, hyperosmotic salinity response
Component cell projection, cytoplasm, ...
Function identical protein binding, lipid binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (78)    Tissues (25)    Images (23)
Theiler Stages: 22, 23, 24, 25, 27, 28
Assay TypeResults
RNA in situ 69
Western blot 9
cDNA source data(63)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(63) cDNA(63)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000019487 (Evidence)
Entrez Gene106628 (Evidence)
UniGene37368
DFCITC1578096, TC1595067, TC1626753
DoTSDT.488595, DT.99849048
NIA Mouse Gene IndexU018149
Consensus CDS ProjectCCDS28930.1
International Mouse Knockout Project StatusTrip10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 106628 NCBI Gene Model | MGI Sequence Detail 14247 C57BL/6J ±  kb
transcript NM_001242389 RefSeq | MGI Sequence Detail 2458 C57BL/6 
polypeptide Q8CJ53 UniProt | EBI | MGI Sequence Detail 603 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(12) UniProt(1)
Polymorphisms SNPs within 2kb(54 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001060 FCH domain
InterPro IPR001452 Src homology-3 domain
Protein Ontology PR:000016670 cdc42-interacting protein 4
Graphical View of Protein Domain Structure
References (Earliest) J:77381 Wang L, et al., Identification and genetic analysis of human and mouse activated Cdc42 interacting protein-4 isoforms. Biochem Biophys Res Commun. 2002 May 24;293(5):1426-30
(Latest) J:202363 Chen Y, et al., Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling. Blood. 2013 Sep 5;122(10):1695-706
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory