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Clic6 Gene Detail
Summary
  • Symbol
    Clic6
  • Name
    chloride intracellular channel 6
  • Synonyms
    5730466J16Rik, CLIC1L
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146607
    NCBI Gene: 209195
  • Gene Overview
    MyGene.info: CLIC6
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:92498147-92541241 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 53.64 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    174 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2146607
protein coding gene Chr16:92485736-92541243 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023058
protein coding gene Chr16:93571671-93633637 (+)
A/J MGP_AJ_G0023026
protein coding gene Chr16:89190721-89247530 (+)
AKR/J MGP_AKRJ_G0022996
protein coding gene Chr16:91913702-91976288 (+)
BALB/cJ MGP_BALBcJ_G0023028
protein coding gene Chr16:89720342-89776104 (+)
C3H/HeJ MGP_C3HHeJ_G0022789
protein coding gene Chr16:92452126-92507955 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023475
protein coding gene Chr16:96564418-96623352 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020977
protein coding gene Chr16:86872987-86932170 (+)
CAST/EiJ MGP_CASTEiJ_G0022308
protein coding gene Chr16:93041683-93100661 (+)
CBA/J MGP_CBAJ_G0022758
protein coding gene Chr16:100708328-100768513 (+)
DBA/2J MGP_DBA2J_G0022892
protein coding gene Chr16:89098139-89154091 (+)
FVB/NJ MGP_FVBNJ_G0022866
protein coding gene Chr16:88222171-88278374 (+)
LP/J MGP_LPJ_G0022962
protein coding gene Chr16:93266310-93323822 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022887
protein coding gene Chr16:105208669-105269000 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023493
protein coding gene Chr16:92414477-92471041 (+)
PWK/PhJ MGP_PWKPhJ_G0022053
protein coding gene Chr16:89295775-89352577 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021883
protein coding gene Chr16:91987390-92048080 (+)
WSB/EiJ MGP_WSBEiJ_G0022360
protein coding gene Chr16:92659878-92718074 (+)



Homology
more
  • Human Ortholog
    CLIC6, chloride intracellular channel 6
  • Vertebrate Orthologs
    7
  • Human Ortholog
    CLIC6, chloride intracellular channel 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CLIC1L
  • Links
    NCBI Gene ID: 54102
    neXtProt AC: NX_Q96NY7
    UniProt: Q96NY7

  • Chr Location
    21q22.12; chr21:34668953-34718227 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 209195 NCBI Gene Model | MGI Sequence Detail 43095 C57BL/6J ±  kb
transcript NM_172469 RefSeq | MGI Sequence Detail 3743 C57BL/6  
polypeptide Q8BHB9 UniProt | EBI | MGI Sequence Detail 596 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 29
    Primer pair 1
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:2146524
References
more
  • Summaries
    All 39
    Developmental Gene Expression 6
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:262380 Watson-Scales S, et al., Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. PLoS Genet. 2018 May;14(5):e1007383

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory