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Rfc4 Gene Detail
Summary
  • Symbol
    Rfc4
  • Name
    replication factor C (activator 1) 4
  • Synonyms
    A1, RFC37
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146571
    NCBI Gene: 106344
  • Gene Overview
    MyGene.info: RFC4
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:23113948-23127730 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 13.93 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    44 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2146571
protein coding gene Chr16:23113943-23127737 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022679
protein coding gene Chr16:20675607-20689407 (-)
A/J MGP_AJ_G0022641
protein coding gene Chr16:19682830-19696701 (-)
AKR/J MGP_AKRJ_G0022615
protein coding gene Chr16:20524983-20539708 (-)
BALB/cJ MGP_BALBcJ_G0022646
protein coding gene Chr16:19888901-19903464 (-)
C3H/HeJ MGP_C3HHeJ_G0022410
protein coding gene Chr16:20645103-20660706 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023095
protein coding gene Chr16:21160403-21177895 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020613
protein coding gene Chr16:20317502-20332334 (-)
CAST/EiJ MGP_CASTEiJ_G0021939
protein coding gene Chr16:20617554-20632932 (-)
CBA/J MGP_CBAJ_G0022381
protein coding gene Chr16:22028587-22044591 (-)
DBA/2J MGP_DBA2J_G0022513
protein coding gene Chr16:19642350-19657084 (-)
FVB/NJ MGP_FVBNJ_G0022489
protein coding gene Chr16:19636536-19650524 (-)
LP/J MGP_LPJ_G0022581
protein coding gene Chr16:20469384-20483119 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022508
protein coding gene Chr16:21567642-21585452 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023107
protein coding gene Chr16:20475340-20491044 (-)
PWK/PhJ MGP_PWKPhJ_G0021678
protein coding gene Chr16:19912232-19926679 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021509
protein coding gene Chr16:20210626-20225812 (-)
WSB/EiJ MGP_WSBEiJ_G0021983
protein coding gene Chr16:20420817-20439564 (-)



Homology
more
  • Human Ortholog
    RFC4, replication factor C subunit 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RFC4, replication factor C subunit 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    A1, RFC37
  • Links
    NCBI Gene ID: 5984
    neXtProt AC: NX_P35249
    UniProt: P35249

  • Chr Location
    3q27.3; chr3:186789892-186806695 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 106344 NCBI Gene Model | MGI Sequence Detail 13783 C57BL/6J ±  kb
transcript NM_145480 RefSeq | MGI Sequence Detail 1231 NMRI  
polypeptide Q99J62 UniProt | EBI | MGI Sequence Detail 364 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR003959 ATPase, AAA-type, core
    IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR013748 Replication factor C, C-terminal
Molecular
Reagents
less
  • All nucleic 62
    cDNA 62

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146520
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:202812 Vannier JB, et al., RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication. Science. 2013 Oct 11;342(6155):239-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory