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Rfc4 Gene Detail
Summary
  • Symbol
    Rfc4
  • Name
    replication factor C (activator 1) 4
  • Synonyms
    A1, RFC37
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146571
    NCBI Gene: 106344
  • Gene Overview
    MyGene.info: RFC4
Location & Maps
more
  • Sequence Map
    Chr16:23113943-23127737 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13795 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 13.93 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    RFC4, replication factor C subunit 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RFC4, replication factor C subunit 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    A1, RFC37
  • Links
    NCBI Gene ID: 5984
    neXtProt AC: NX_P35249

  • Chr Location
    3q27.3; chr3:186789892-186806695 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025290 VEGA Gene Model | MGI Sequence Detail 13795 C57BL/6J ±  kb
transcript OTTMUST00000062241 VEGA | MGI Sequence Detail 1279 Not Applicable  
polypeptide OTTMUSP00000030657 VEGA | MGI Sequence Detail 370 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    44 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000013908 replication factor C subunit 4
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR003959 ATPase, AAA-type, core
    IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR013748 Replication factor C, C-terminal
Molecular
Reagents
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  • All nucleic 61
    cDNA 61

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146520
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:202812 Vannier JB, et al., RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication. Science. 2013 Oct 11;342(6155):239-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory