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Osbpl11 Gene Detail
Summary
  • Symbol
    Osbpl11
  • Name
    oxysterol binding protein-like 11
  • Synonyms
    ORP-11
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146553
    NCBI Gene: 106326
  • Gene Overview
    MyGene.info: OSBPL11
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:33185071-33243312 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 23.71 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    176 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2146553
protein coding gene Chr16:33169767-33243312 (.)
129S1/SvImJ MGP_129S1SvImJ_G0022753
protein coding gene Chr16:31363600-31422906 (+)
A/J MGP_AJ_G0022718
protein coding gene Chr16:29868983-29927212 (+)
AKR/J MGP_AKRJ_G0022691
protein coding gene Chr16:30914049-30974149 (+)
BALB/cJ MGP_BALBcJ_G0022720
protein coding gene Chr16:29969300-30033141 (+)
C3H/HeJ MGP_C3HHeJ_G0022485
protein coding gene Chr16:31037882-31101706 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023169
protein coding gene Chr16:32060013-32123633 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020687
protein coding gene Chr16:30204902-30264939 (+)
CAST/EiJ MGP_CASTEiJ_G0022013
protein coding gene Chr16:31188858-31252403 (+)
CBA/J MGP_CBAJ_G0022455
protein coding gene Chr16:33317881-33393729 (+)
DBA/2J MGP_DBA2J_G0022588
protein coding gene Chr16:29678657-29738626 (+)
FVB/NJ MGP_FVBNJ_G0022563
protein coding gene Chr16:29675281-29737677 (+)
LP/J MGP_LPJ_G0022655
protein coding gene Chr16:31106133-31168910 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022582
protein coding gene Chr16:32737907-32807711 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023181
protein coding gene Chr16:30909698-30973416 (+)
PWK/PhJ MGP_PWKPhJ_G0021754
protein coding gene Chr16:30057195-30116256 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021583
protein coding gene Chr16:30724755-30784708 (+)
WSB/EiJ MGP_WSBEiJ_G0022057
protein coding gene Chr16:30881023-30944810 (+)



Homology
more
  • Human Ortholog
    OSBPL11, oxysterol binding protein like 11
  • Vertebrate Orthologs
    10
  • Human Ortholog
    OSBPL11, oxysterol binding protein like 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ORP11, ORP-11, OSBP12, TCCCIA00292
  • Links
    NCBI Gene ID: 114885
    neXtProt AC: NX_Q9BXB4
    UniProt: Q9BXB4

  • Chr Location
    3q21.2; chr3:125528858-125595537 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022807 Ensembl Gene Model | MGI Sequence Detail 58242 C57BL/6J ±  kb
transcript ENSMUST00000039733 Ensembl | MGI Sequence Detail 4521 Not Applicable  
polypeptide ENSMUSP00000039632 Ensembl | MGI Sequence Detail 757 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR000648 Oxysterol-binding protein
    IPR018494 Oxysterol-binding protein, conserved site
    IPR037239 Oxysterol-binding protein superfamily
    IPR011993 PH-like domain superfamily
    IPR001849 Pleckstrin homology domain
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146378
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory