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Slc7a4 Gene Detail
Summary
  • Symbol
    Slc7a4
  • Name
    solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
  • Synonyms
    MGC:27672
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146512
    NCBI Gene: 224022
  • Gene Overview
    MyGene.info: SLC7A4
Location & Maps
more
  • Sequence Map
    Chr16:17572018-17576998 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4981 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SLC7A4, solute carrier family 7 member 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SLC7A4, solute carrier family 7 member 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CAT4, CAT-4, HCAT3, VH
  • Links
    NCBI Gene ID: 6545
    neXtProt AC: NX_O43246

  • Chr Location
    22q11.21; chr22:21028718-21032558 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035925 VEGA Gene Model | MGI Sequence Detail 4981 C57BL/6J ±  kb
transcript OTTMUST00000092151 VEGA | MGI Sequence Detail 3281 Not Applicable  
polypeptide OTTMUSP00000050863 VEGA | MGI Sequence Detail 635 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    36 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000015200 cationic amino acid transporter 4
  • InterPro Domains
    IPR002293 Amino acid/polyamine transporter I
    IPR029485 Cationic amino acid transporter, C-terminal
Molecular
Reagents
less
  • All nucleic 35
    cDNA 33
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 26
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
  • Latest
    J:230261 Racedo SE, et al., Mouse and human CRKL is dosage sensitive for cardiac outflow tract formation. Am J Hum Genet. 2015 Feb 5;96(2):235-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory