Slc7a4
Gene Detail

Symbol Name ID

Slc7a4 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 MGI:2146512

Synonyms

MGC:27672

Feature Type

protein coding gene

Genetic Map

Chromosome 16

10.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr16:17572018-17576998 bp, - strand From VEGA annotation of GRCm38   4981 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:20883  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: amino acid transporter
Gene Tree: Slc7a4

Human homologs

Human Homolog		SLC7A4, solute carrier family 7 (orphan transporter), member 4
NCBI Gene ID		6545
neXtProt AC		NX_O43246
Human Synonyms		CAT4, CAT-4, HCAT3, VH
Human Chr (Location)		22q11.21; chr22:21383007-21386847 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	amino acid transmembrane transport, amino acid transport, ...
Component	integral to membrane, membrane
Function	amino acid transmembrane transporter activity

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (284)    Tissues (116)    Images (70)
Theiler Stages: 22, 23, 24, 26, 28

Assay Type	Results
RNA in situ	264
RT-PCR	20

cDNA source data(41)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(43) cDNA(41) Primer pair(2)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000035925 (Evidence)
Ensembl Gene Model	ENSMUSG00000022756 (Evidence)
Entrez Gene	224022 (Evidence)
UniGene	298878
DFCI	TC1577911, TC1589106, TC1592269
DoTS	DT.101230930, DT.101344467, DT.94200553, DT.97359005
NIA Mouse Gene Index	U036847
Consensus CDS Project	CCDS28008.1
International Mouse Knockout Project Status	Slc7a4

Sequences

Length	Strain/Species
genomic	OTTMUSG00000035925	VEGA Gene Model | MGI Sequence Detail	4981	C57BL/6J
transcript	OTTMUST00000092151	VEGA | MGI Sequence Detail	3281	Not Applicable
polypeptide	OTTMUSP00000050863	VEGA | MGI Sequence Detail	635	Not Applicable

All sequences(51) RefSeq(2) UniProt(6)

Polymorphisms

SNPs(22 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002293	Amino acid/polyamine transporter I
InterPro	IPR015606	Cationic amino acid transporter
Protein Ontology	PR:000015200	cationic amino acid transporter 4

References

(Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(29)