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Slc7a4
Gene Detail
 Symbol
Name
ID
Slc7a4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
MGI:2146512
Synonyms MGC:27672
Feature Type protein coding gene
Genetic Map
Chromosome 16
10.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr16:17572018-17576998 bp, - strand
From VEGA annotation of GRCm38

  4981 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20883  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: amino acid transporter
Gene Tree: Slc7a4

Human
homologs
Human Homolog SLC7A4, solute carrier family 7, member 4
NCBI Gene ID 6545
neXtProt AC  NX_O43246
Human Synonyms  CAT4, CAT-4, HCAT3, VH
Human Chr (Location)  22q11.21; chr22:21028718-21032874 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Slc7a4 interacts with 170 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process amino acid transmembrane transport, amino acid transport, ...
Component integral component of membrane, membrane
Function amino acid transmembrane transporter activity
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (306)    Tissues (139)    Images (71)
Theiler Stages: 22, 23, 24, 26, 27, 28
Assay TypeResults
RNA in situ 286
RT-PCR 20
cDNA source data(33)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(35) cDNA(33) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000035925 (Evidence)
Ensembl Gene ModelENSMUSG00000022756 (Evidence)
Entrez Gene224022 (Evidence)
UniGene298878
DFCITC1577911, TC1589106, TC1592269
DoTSDT.101230930, DT.101344467, DT.94200553, DT.97359005
NIA Mouse Gene IndexU036847
Consensus CDS ProjectCCDS28008.1
International Mouse Knockout Project StatusSlc7a4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035925 VEGA Gene Model | MGI Sequence Detail 4981 C57BL/6J ±  kb
transcript OTTMUST00000092151 VEGA | MGI Sequence Detail 3281 Not Applicable 
polypeptide OTTMUSP00000050863 VEGA | MGI Sequence Detail 635 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(10) UniProt(6)
Polymorphisms SNPs within 2kb(36 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002293 Amino acid/polyamine transporter I
Protein Ontology PR:000015200 cationic amino acid transporter 4
References (Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory