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Vps8 Gene Detail
Summary
  • Symbol
    Vps8
  • Name
    VPS8 CORVET complex subunit
  • Synonyms
    mKIAA0804
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146407
    NCBI Gene: 209018
Location & Maps
more
  • Sequence Map
    Chr16:21423118-21644680 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      221563 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 12.69 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    VPS8, VPS8, CORVET complex subunit
  • Vertebrate Orthologs
    10
  • Human Ortholog
    VPS8, VPS8, CORVET complex subunit
    Orthology source: HomoloGene, HGNC
  • Synonyms
    KIAA0804
  • Links
    NCBI Gene ID: 23355
    neXtProt AC: NX_Q8N3P4

  • Chr Location
    3q27.2; chr3:184812137-185052614 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 44592
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: VPS8
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027225 VEGA Gene Model | MGI Sequence Detail 221563 C57BL/6J ±  kb
transcript OTTMUST00000068636 VEGA | MGI Sequence Detail 4935 Not Applicable  
polypeptide OTTMUSP00000034744 VEGA | MGI Sequence Detail 1427 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1180 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 65
    cDNA 65

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146573
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:222663 Perini ED, et al., Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations. Traffic. 2014 Dec;15(12):1366-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory