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Deptor Gene Detail
Summary
  • Symbol
    Deptor
  • Name
    DEP domain containing MTOR-interacting protein
  • Synonyms
    4731402B04Rik, 9130412E02Rik, D15Ertd336e, D15Ertd597e, Depdc6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146322
    NCBI Gene: 97998
  • Gene Overview
    MyGene.info: DEPTOR
Location & Maps
more
  • Sequence Map
    Chr15:55112317-55259271 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      146955 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    DEPTOR, DEP domain containing MTOR-interacting protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DEPTOR, DEP domain containing MTOR-interacting protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    DEP.6, DEPDC6
  • Links
    NCBI Gene ID: 64798
    neXtProt AC: NX_Q8TB45

  • Chr Location
    8q24.12; chr8:119873655-120050918 (+)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from multigenic genotypes
    22 phenotype references
  • All Mutations and Alleles
    27
  • Chemically induced (other)
    3
  • Gene trapped
    20
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Deptor
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024429 VEGA Gene Model | MGI Sequence Detail 146955 C57BL/6J ±  kb
transcript OTTMUST00000059891 VEGA | MGI Sequence Detail 8547 Not Applicable  
polypeptide OTTMUSP00000029173 VEGA | MGI Sequence Detail 409 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1243 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000029102 DEP domain-containing mTOR-interacting protein
  • InterPro Domains
    IPR000591 DEP domain
    IPR001478 PDZ domain
    IPR011991 Winged helix-turn-helix DNA-binding domain
Molecular
Reagents
less
  • All nucleic 17
    cDNA 15
    Primer pair 2

    Microarray probesets 9
Other
Accession IDs
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MGI:1196436, MGI:1289169, MGI:1918827, MGI:1921823
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 2
    Phenotypes 22
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:224980 Lee KY, et al., Tbx15 controls skeletal muscle fibre-type determination and muscle metabolism. Nat Commun. 2015;6:8054

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory