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Lmf2 Gene Detail
Summary
  • Symbol
    Lmf2
  • Name
    lipase maturation factor 2
  • Synonyms
    Tmem112b, Tmem153
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146015
    NCBI Gene: 105847
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:89351004-89355659 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 44.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2146015
protein coding gene Chr15:89351004-89355659 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022227
protein coding gene Chr15:90542295-90546950 (-)
A/J MGP_AJ_G0022186
protein coding gene Chr15:87078227-87082882 (-)
AKR/J MGP_AKRJ_G0022161
protein coding gene Chr15:89653122-89657777 (-)
BALB/cJ MGP_BALBcJ_G0022192
protein coding gene Chr15:87182815-87187470 (-)
C3H/HeJ MGP_C3HHeJ_G0021962
protein coding gene Chr15:89653794-89658449 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022637
protein coding gene Chr15:93830267-93834922 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020162
protein coding gene Chr15:83306316-83310969 (-)
CAST/EiJ MGP_CASTEiJ_G0021484
protein coding gene Chr15:90429045-90433700 (-)
CBA/J MGP_CBAJ_G0021929
protein coding gene Chr15:97016011-97020666 (-)
DBA/2J MGP_DBA2J_G0022056
protein coding gene Chr15:86529297-86533952 (-)
FVB/NJ MGP_FVBNJ_G0022035
protein coding gene Chr15:85594109-85598764 (-)
LP/J MGP_LPJ_G0022127
protein coding gene Chr15:90699859-90704514 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022055
protein coding gene Chr15:101413708-101418363 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022652
protein coding gene Chr15:89691509-89696164 (-)
PWK/PhJ MGP_PWKPhJ_G0021225
protein coding gene Chr15:86590723-86595378 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021059
protein coding gene Chr15:89440434-89445082 (-)
WSB/EiJ MGP_WSBEiJ_G0021533
protein coding gene Chr15:90180516-90185171 (-)



Homology
more
  • Human Ortholog
    LMF2, lipase maturation factor 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    LMF2, lipase maturation factor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TMEM112B, TMEM153
  • Links
    NCBI Gene ID: 91289
    neXtProt AC: NX_Q9BU23
    UniProt: Q9BU23

  • Chr Location
    22q13.33; chr22:50502947-50507840 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11251
    1 human;1 mouse;1 rat;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LMF2
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    3 involving Lmf2
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 105847 NCBI Gene Model | MGI Sequence Detail 4656 C57BL/6J ±  kb
transcript NM_178919 RefSeq | MGI Sequence Detail 2906 C57BL/6  
polypeptide Q8C3X8 UniProt | EBI | MGI Sequence Detail 702 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 99
    cDNA 99

    Microarray probesets 3
References
more
  • Summaries
    All 44
    Diseases 1
    Gene Ontology 2
    Phenotypes 21
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/16/2019
MGI 6.13
The Jackson Laboratory