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Lmf2 Gene Detail
Summary
  • Symbol
    Lmf2
  • Name
    lipase maturation factor 2
  • Synonyms
    Tmem112b, Tmem153
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146015
    NCBI Gene: 105847
Location & Maps
more
  • Sequence Map
    Chr15:89351004-89355659 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4656 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 44.84 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    LMF2, lipase maturation factor 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    LMF2, lipase maturation factor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TMEM112B, TMEM153
  • Links
    NCBI Gene ID: 91289
    neXtProt AC: NX_Q9BU23

  • Chr Location
    22q13.33; chr22:50502947-50507840 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 11251
    1 human;1 mouse;1 rat;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: LMF2
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    3 involving Lmf2
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 105847 NCBI Gene Model | MGI Sequence Detail 4656 C57BL/6J ±  kb
transcript NM_178919 RefSeq | MGI Sequence Detail 2906 C57BL/6  
polypeptide Q8C3X8 UniProt | EBI | MGI Sequence Detail 702 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    24 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000009857 lipase maturation factor 2
  • InterPro Domains
    IPR009613 Lipase maturation factor
Molecular
Reagents
less
  • All nucleic 98
    cDNA 98

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Diseases 1
    Gene Ontology 3
    Phenotypes 21
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory