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Amigo2 Gene Detail
Summary
  • Symbol
    Amigo2
  • Name
    adhesion molecule with Ig like domain 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145995
    NCBI Gene: 105827
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:97244125-97247287 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 52.91 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    37 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145995
protein coding gene Chr15:97244074-97247287 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022274
protein coding gene Chr15:98888508-98891755 (-)
A/J MGP_AJ_G0022233
protein coding gene Chr15:94985611-94988824 (-)
AKR/J MGP_AKRJ_G0022208
protein coding gene Chr15:97864200-97867414 (-)
BALB/cJ MGP_BALBcJ_G0022239
protein coding gene Chr15:95200885-95204098 (-)
C3H/HeJ MGP_C3HHeJ_G0022009
protein coding gene Chr15:97895352-97898565 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022684
protein coding gene Chr15:102531601-102534814 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020210
protein coding gene Chr15:90953789-90957009 (-)
CAST/EiJ MGP_CASTEiJ_G0021531
protein coding gene Chr15:98785642-98788856 (-)
CBA/J MGP_CBAJ_G0021976
protein coding gene Chr15:105973055-105976269 (-)
DBA/2J MGP_DBA2J_G0022103
protein coding gene Chr15:94429162-94432376 (-)
FVB/NJ MGP_FVBNJ_G0022082
protein coding gene Chr15:93423428-93426453 (-)
LP/J MGP_LPJ_G0022174
protein coding gene Chr15:98997993-99001200 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022102
protein coding gene Chr15:110120386-110123599 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022699
protein coding gene Chr15:97981465-97984680 (-)
PWK/PhJ MGP_PWKPhJ_G0021272
protein coding gene Chr15:94522268-94525431 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021106
protein coding gene Chr15:97776819-97780040 (-)
WSB/EiJ MGP_WSBEiJ_G0021580
protein coding gene Chr15:98506766-98509984 (-)



Homology
more
  • Human Ortholog
    AMIGO2, adhesion molecule with Ig like domain 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    AMIGO2, adhesion molecule with Ig like domain 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ALI1, AMIGO-2, DEGA
  • Links
    NCBI Gene ID: 347902
    neXtProt AC: NX_Q86SJ2
    UniProt: Q86SJ2

  • Chr Location
    12q13.11; chr12:47075707-47080826 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048218 Ensembl Gene Model | MGI Sequence Detail 3163 C57BL/6J ±  kb
transcript ENSMUST00000229890 Ensembl | MGI Sequence Detail 2998 Not Applicable  
polypeptide ENSMUSP00000155019 Ensembl | MGI Sequence Detail 519 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146206
References
more
  • Summaries
    All 51
    Developmental Gene Expression 7
    Diseases 1
    Gene Ontology 7
    Phenotypes 19
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:264089 Sonzogni O, et al., Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo. PLoS Biol. 2018 Jun;16(6):e2004049

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory