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Amigo2 Gene Detail
Summary
  • Symbol
    Amigo2
  • Name
    adhesion molecule with Ig like domain 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145995
    NCBI Gene: 105827
Location & Maps
more
  • Sequence Map
    Chr15:97244074-97247287 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3214 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    AMIGO2, adhesion molecule with Ig-like domain 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    AMIGO2, adhesion molecule with Ig-like domain 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ALI1, AMIGO-2, DEGA
  • Links
    NCBI Gene ID: 347902
    neXtProt AC: NX_Q86SJ2

  • Chr Location
    12q13.11; chr12:47075707-47080826 (-)  GRCh38.p2

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    18 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Amigo2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 105827 NCBI Gene Model | MGI Sequence Detail 3214 C57BL/6J ±  kb
transcript NM_178114 RefSeq | MGI Sequence Detail 3214 C57BL/6  
polypeptide Q80ZD9 UniProt | EBI | MGI Sequence Detail 519 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    38 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146206
References
more
  • Summaries
    All 27
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 5
    Phenotypes 18
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:214095 Osipovich AB, et al., Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3. Development. 2014 Aug;141(15):2939-49

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory