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Ano6
Gene Detail
Symbol

Name
ID
Ano6
anoctamin 6
MGI:2145890
Synonyms
2900059G15Rik, F730003B03Rik, Tmem16f
Feature Type
protein coding gene
Genetic Map
Chromosome 15
50.66 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:95790843-95975464 bp, + strand
From Ensembl annotation of GRCm38

  184622 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:27888  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ano6

Human
homologs
Human Homolog ANO6, anoctamin 6
NCBI Gene ID 196527
neXtProt AC  NX_Q4KMQ2
Human Synonyms  BDPLT7, SCTS, TMEM16F
Human Chr (Location)  12q12; chr12:45215987-45440404 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ANO6
Mutations,
alleles, and
phenotypes
All mutations/alleles(23) : Gene trapped(18) Radiation induced(1) Targeted(4)
Genomic Mutations involving Ano6 (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit impaired platelet coagulation with increased bleeding time. Mice homozygous for a different knock out allele or gene trap exhibit decreased bone mineral deposition and skeletal abnormalities.
 
Interactions
Ano6 interacts with 326 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (113)    Tissues (101)    Images (30)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 113
cDNA source data(177)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(177) cDNA(177)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000064210 (Evidence)
Entrez Gene105722 (Evidence)
UniGene38087
DFCITC1624703, TC1622479, TC1575272, TC1639671
DoTSDT.101196571, DT.97353969, DT.91295893, DT.491093
NIA Mouse Gene IndexU016604
Consensus CDS ProjectCCDS37184.1
International Mouse Knockout Project StatusAno6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000064210 Ensembl Gene Model | MGI Sequence Detail 184622 C57BL/6J ±  kb
transcript ENSMUST00000071874 Ensembl | MGI Sequence Detail 5640 Not Applicable 
polypeptide ENSMUSP00000071770 Ensembl | MGI Sequence Detail 911 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(16) UniProt(1)
Polymorphisms
SNPs within 2kb(2014 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007632 Anoctamin/TMEM 16
Protein Ontology PR:000004061 anoctamin-6
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:213003 Suzuki T, et al., Functional swapping between transmembrane proteins TMEM16A and TMEM16F. J Biol Chem. 2014 Mar 14;289(11):7438-47
All references(42)
Other
accession IDs
MGI:1920265, MGI:2146238

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory