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Ankrd28 Gene Detail
Summary
  • Symbol
    Ankrd28
  • Name
    ankyrin repeat domain 28
  • Synonyms
    E430019N21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145661
    NCBI Gene: 105522
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:31698768-31830415 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 19.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    185 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145661
protein coding gene Chr14:31698768-31830651 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021134
protein coding gene Chr14:24894924-25029742 (-)
A/J MGP_AJ_G0021082
protein coding gene Chr14:23958943-24091304 (-)
AKR/J MGP_AKRJ_G0021059
protein coding gene Chr14:25084393-25216001 (-)
BALB/cJ MGP_BALBcJ_G0021086
protein coding gene Chr14:24094129-24228207 (-)
C3H/HeJ MGP_C3HHeJ_G0020869
protein coding gene Chr14:24954603-25090960 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021518
protein coding gene Chr14:25874754-26016466 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019081
protein coding gene Chr14:24026978-24166055 (-)
CAST/EiJ MGP_CASTEiJ_G0020394
protein coding gene Chr14:24750115-24890182 (-)
CBA/J MGP_CBAJ_G0020836
protein coding gene Chr14:26852867-26986909 (-)
DBA/2J MGP_DBA2J_G0020958
protein coding gene Chr14:23993496-24127468 (-)
FVB/NJ MGP_FVBNJ_G0020942
protein coding gene Chr14:23947163-24079309 (-)
LP/J MGP_LPJ_G0021027
protein coding gene Chr14:25219808-25354287 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020968
protein coding gene Chr14:26111808-26256877 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021551
protein coding gene Chr14:24852107-24991007 (-)
PWK/PhJ MGP_PWKPhJ_G0020142
protein coding gene Chr14:23458684-23596872 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019966
protein coding gene Chr14:24466443-24607044 (-)
WSB/EiJ MGP_WSBEiJ_G0020449
protein coding gene Chr14:24926569-25062990 (-)



Homology
more
  • Human Ortholog
    ANKRD28, ankyrin repeat domain 28
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ANKRD28, ankyrin repeat domain 28
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PITK, PPP1R65
  • Links
    NCBI Gene ID: 23243
    neXtProt AC: NX_O15084
    UniProt: O15084

  • Chr Location
    3p25.1; chr3:15667236-15859814 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 105522 NCBI Gene Model | MGI Sequence Detail 131648 C57BL/6J ±  kb
transcript NM_001024604 RefSeq | MGI Sequence Detail 5229 C57BL/6  
polypeptide Q505D1 UniProt | EBI | MGI Sequence Detail 1053 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000004047 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
  • InterPro Domains
    IPR002110 Ankyrin repeat
    IPR020683 Ankyrin repeat-containing domain
    IPR036770 Ankyrin repeat-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 7
Other
Accession IDs
less
MGI:2145679
References
more
  • Summaries
    All 29
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:34960 Chambers DM, et al., Isolation and mapping of novel mouse brain cDNA clones containing trinucleotide repeats, and demonstration of novel alleles in recombinant inbred strains. Genome Res. 1996 Aug;6(8):715-23
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/01/2019
MGI 6.14
The Jackson Laboratory