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Exoc5
Gene Detail
Symbol

Name
ID
Exoc5
exocyst complex component 5
MGI:2145645
Synonyms
PRO1912, SEC10, Sec10l1
Feature Type
protein coding gene
Genetic Map
Chromosome 14
25.36 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:49012146-49066653 bp, - strand
From VEGA annotation of GRCm38

  54508 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38195  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: EXOC5
Protein SuperFamily: exocyst complex, component Sec10
Gene Tree: Exoc5

Human
homologs
EXOC5, exocyst complex component 5
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 10640
neXtProt AC: NX_O00471

Human Synonyms: HSEC10, PRO1912, SEC10, SEC10L1, SEC10P

Human Chr (Location): 14q22.3; chr14:57202476-57268899 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(10) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Exoc5 interacts with 314 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process exocytosis, protein transport, ...
Component cytoplasm, cytosol
Function protein N-terminus binding, Ral GTPase binding
External Resources: FuncBase
Expression
cDNA source data(13)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase exoc5    NEW 
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000034599 (Evidence)
Ensembl Gene Model ENSMUSG00000061244 (Evidence)
Entrez Gene 105504 (Evidence)
DFCI TC1664595, TC1578253, TC1598222
NIA Mouse Gene Index U035489
Consensus CDS Project CCDS49474.1
International Mouse Phenotyping Consortium Status Exoc5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034599 VEGA Gene Model | MGI Sequence Detail 54508 C57BL/6J ±  kb
transcript OTTMUST00000087772 VEGA | MGI Sequence Detail 4643 Not Applicable 
polypeptide OTTMUSP00000047784 VEGA | MGI Sequence Detail 708 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(7) UniProt(6)
Polymorphisms
SNPs within 2kb(266 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009976 Exocyst complex component Sec10-like
Protein Ontology PR:000007252 exocyst complex component 5
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:150915 Saito T, et al., Involvement of Exoc3l, a protein structurally related to the exocyst subunit Sec6, in insulin secretion. Biomed Res. 2008 Apr;29(2):85-91
All references(32)
Other
accession IDs
MGI:2145643, MGI:2684922

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory