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Mtmr6
Gene Detail
Symbol

Name
ID
Mtmr6
myotubularin related protein 6
MGI:2145637
Synonyms
4022440C11Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 14
31.62 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:60265205-60302370 bp, + strand
From Ensembl annotation of GRCm38

  37166 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55842  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MTMR6
Gene Tree: Mtmr6

Human
homologs
MTMR6, myotubularin related protein 6
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9107
neXtProt AC: NX_Q9Y217

Human Chr (Location): 13q12; chr13:25246201-25287566 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Gene trapped(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Mtmr6 interacts with 289 markers (Mir1b, Mir7-1, Mir9-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (147)    Tissues (104)    Images (34)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 147
cDNA source data(106)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase mtmr6 ; ZFIN mtmr6    NEW 
Molecular
reagents
All nucleic(106) cDNA(106)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000021987 (Evidence)
Entrez Gene 219135 (Evidence)
UniGene 247007
DFCI TC1575220, TC1605271
DoTS DT.101394554, DT.101394553, DT.94342964, DT.533701
NIA Mouse Gene Index U015713
EC 3.1.3.-
Consensus CDS Project CCDS27176.1
International Mouse Phenotyping Consortium Status Mtmr6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021987 Ensembl Gene Model | MGI Sequence Detail 37166 C57BL/6J ±  kb
transcript ENSMUST00000022563 Ensembl | MGI Sequence Detail 3836 Not Applicable 
polypeptide ENSMUSP00000022563 Ensembl | MGI Sequence Detail 617 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(142 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010569 Myotubularin-related
InterPro IPR011993 Pleckstrin homology-like domain
InterPro IPR016130 Protein-tyrosine phosphatase, active site
Protein Ontology PR:000010739 myotubularin-related protein 6
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:207393 Maekawa M, et al., Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E978-87
All references(31)
Other
accession IDs
MGI:2145755

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory