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Kctd9 Gene Detail
Summary
  • Symbol
    Kctd9
  • Name
    potassium channel tetramerisation domain containing 9
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145579
    NCBI Gene: 105440
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:67953536-67979760 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 34.66 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    125 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145579
protein coding gene Chr14:67953386-67979760 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021505
protein coding gene Chr14:62460979-62487353 (+)
A/J MGP_AJ_G0021464
protein coding gene Chr14:60959163-60985537 (+)
AKR/J MGP_AKRJ_G0021440
protein coding gene Chr14:63039996-63066357 (+)
BALB/cJ MGP_BALBcJ_G0021470
protein coding gene Chr14:60954032-60980407 (+)
C3H/HeJ MGP_C3HHeJ_G0021247
protein coding gene Chr14:62767449-62793803 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021909
protein coding gene Chr14:65298405-65324778 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019449
protein coding gene Chr14:58867204-58894202 (+)
CAST/EiJ MGP_CASTEiJ_G0020764
protein coding gene Chr14:59265794-59292222 (+)
CBA/J MGP_CBAJ_G0021214
protein coding gene Chr14:67307091-67333457 (+)
DBA/2J MGP_DBA2J_G0021337
protein coding gene Chr14:60592289-60618507 (+)
FVB/NJ MGP_FVBNJ_G0021316
protein coding gene Chr14:59997013-60023369 (+)
LP/J MGP_LPJ_G0021412
protein coding gene Chr14:63514615-63540989 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021345
protein coding gene Chr14:66282961-66311621 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021932
protein coding gene Chr14:62270759-62297140 (+)
PWK/PhJ MGP_PWKPhJ_G0020508
protein coding gene Chr14:57357508-57383731 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020341
protein coding gene Chr14:58213668-58240265 (+)
WSB/EiJ MGP_WSBEiJ_G0020817
protein coding gene Chr14:62599618-62626006 (+)



Homology
more
  • Human Ortholog
    KCTD9, potassium channel tetramerization domain containing 9
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KCTD9, potassium channel tetramerization domain containing 9
  • Synonyms
    BTBD27
  • Links
    NCBI Gene ID: 54793
    neXtProt AC: NX_Q7L273
    UniProt: Q7L273

  • Chr Location
    8p21.2; chr8:25424357-25458468 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit impaired NK cell development and effector function.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 105440 NCBI Gene Model | MGI Sequence Detail 26225 C57BL/6J ±  kb
    transcript NM_001285933 RefSeq | MGI Sequence Detail 3451 C57BL/6  
    polypeptide Q80UN1 UniProt | EBI | MGI Sequence Detail 339 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 47
      cDNA 47

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2145704
    References
    more
    • Summaries
      All 29
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 8
    • Earliest
      J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
    • Latest
      J:281803 Zhang X, et al., Kctd9 Deficiency Impairs Natural Killer Cell Development and Effector Function. Front Immunol. 2019;10:744

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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    Funding Information
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    last database update
    06/14/2022
    MGI 6.19
    The Jackson Laboratory