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Depdc1b Gene Detail
Summary
  • Symbol
    Depdc1b
  • Name
    DEP domain containing 1B
  • Synonyms
    XTP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145425
    NCBI Gene: 218581
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:108316013-108389566 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 59.69 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    606 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145425
protein coding gene Chr13:108316013-108407782 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020926
protein coding gene Chr13:110625315-110715823 (+)
A/J MGP_AJ_G0020875
protein coding gene Chr13:106272646-106359312 (+)
AKR/J MGP_AKRJ_G0020851
protein coding gene Chr13:109476254-109568858 (+)
BALB/cJ MGP_BALBcJ_G0020876
protein coding gene Chr13:106996139-107082183 (+)
C3H/HeJ MGP_C3HHeJ_G0020665
protein coding gene Chr13:109270744-109358612 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021311
protein coding gene Chr13:113937203-114045243 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018880
protein coding gene Chr13:101732711-101818660 (+)
CAST/EiJ MGP_CASTEiJ_G0020184
protein coding gene Chr13:108796332-108884845 (+)
CBA/J MGP_CBAJ_G0020627
protein coding gene Chr13:118351096-118442339 (+)
DBA/2J MGP_DBA2J_G0020750
protein coding gene Chr13:106029556-106115140 (+)
FVB/NJ MGP_FVBNJ_G0020733
protein coding gene Chr13:104681428-104769420 (+)
LP/J MGP_LPJ_G0020825
protein coding gene Chr13:110687785-110789497 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020761
protein coding gene Chr13:118735860-118822158 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021349
protein coding gene Chr13:108957340-109044116 (+)
PWK/PhJ MGP_PWKPhJ_G0019937
protein coding gene Chr13:104720005-104806631 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019759
protein coding gene Chr13:105201537-105293593 (+)
WSB/EiJ MGP_WSBEiJ_G0020242
protein coding gene Chr13:109498823-109587846 (+)



Homology
more
  • Human Ortholog
    DEPDC1B, DEP domain containing 1B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DEPDC1B, DEP domain containing 1B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BRCC3, XTP1
  • Links
    NCBI Gene ID: 55789
    neXtProt AC: NX_Q8WUY9
    UniProt: Q8WUY9

  • Chr Location
    5q12.1; chr5:60596912-60700166 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 218581 NCBI Gene Model | MGI Sequence Detail 73554 C57BL/6J ±  kb
transcript NM_178683 RefSeq | MGI Sequence Detail 2530 C57BL/6  
polypeptide Q8BH88 UniProt | EBI | MGI Sequence Detail 529 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 2
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory