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Dhx29 Gene Detail
Summary
  • Symbol
    Dhx29
  • Name
    DEAH (Asp-Glu-Ala-His) box polypeptide 29
  • Synonyms
    E130202M19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145374
    NCBI Gene: 218629
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:112927793-112969187 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 63.93 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    451 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2145374
protein coding gene Chr13:112927454-112969432 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020942
protein coding gene Chr13:115520527-115569659 (+)
A/J MGP_AJ_G0020892
protein coding gene Chr13:110909301-110951410 (+)
AKR/J MGP_AKRJ_G0020867
protein coding gene Chr13:114256661-114298044 (+)
BALB/cJ MGP_BALBcJ_G0020892
protein coding gene Chr13:111600643-111642601 (+)
C3H/HeJ MGP_C3HHeJ_G0020681
protein coding gene Chr13:114049970-114092341 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021328
protein coding gene Chr13:118943683-118985013 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018897
protein coding gene Chr13:106196324-106239709 (+)
CAST/EiJ MGP_CASTEiJ_G0020201
protein coding gene Chr13:113674748-113726449 (+)
CBA/J MGP_CBAJ_G0020643
protein coding gene Chr13:123546084-123590249 (+)
DBA/2J MGP_DBA2J_G0020766
protein coding gene Chr13:110618861-110660680 (+)
FVB/NJ MGP_FVBNJ_G0020750
protein coding gene Chr13:109313997-109356749 (+)
LP/J MGP_LPJ_G0020842
protein coding gene Chr13:115561413-115603358 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020778
protein coding gene Chr13:123799158-123847007 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021364
protein coding gene Chr13:113720342-113763449 (+)
PWK/PhJ MGP_PWKPhJ_G0019954
protein coding gene Chr13:109367698-109409995 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019776
protein coding gene Chr13:110029338-110076375 (+)
WSB/EiJ MGP_WSBEiJ_G0020258
protein coding gene Chr13:114313115-114356576 (+)



Homology
more
  • Human Ortholog
    DHX29, DExH-box helicase 29
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DHX29, DExH-box helicase 29
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DDX29
  • Links
    NCBI Gene ID: 54505
    neXtProt AC: NX_Q7Z478
    UniProt: Q7Z478

  • Chr Location
    5q11.2; chr5:55256245-55307693 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10387
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DHX29
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E7.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 218629 NCBI Gene Model | MGI Sequence Detail 41395 C57BL/6J ±  kb
transcript NM_172594 RefSeq | MGI Sequence Detail 4098 Not Specified  
polypeptide Q6PGC1 UniProt | EBI | MGI Sequence Detail 1365 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • EC
  • InterPro Domains
    IPR034730 ATP-dependent RNA helicase DHX29
    IPR011545 DEAD/DEAH box helicase domain
    IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
    IPR011709 Domain of unknown function DUF1605
    IPR007502 Helicase-associated domain
    IPR001650 Helicase, C-terminal
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 17
    cDNA 17

    Microarray probesets 8
Other
Accession IDs
less
MGI:1926111
References
more
  • Summaries
    All 36
    Gene Ontology 6
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory