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Srek1 Gene Detail
Summary
  • Symbol
    Srek1
  • Name
    splicing regulatory glutamine/lysine-rich protein 1
  • Synonyms
    AL118220, Sfrs12, SRrp508, SRrp86
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145245
    NCBI Gene: 218543
  • Gene Overview
    MyGene.info: SREK1
Location & Maps
more
  • Sequence Map
    Chr13:103739348-103774608 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      35261 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 56.16 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SREK1, splicing regulatory glutamic acid and lysine rich protein 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SREK1, splicing regulatory glutamic acid and lysine rich protein 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SFRS12, SRrp508, SRrp86
  • Links
    NCBI Gene ID: 140890
    neXtProt AC: NX_Q8WXA9

  • Chr Location
    5q12.3; chr5:66144218-66183616 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    7
  • Gene trapped
    4
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000061082 VEGA Gene Model | MGI Sequence Detail 35261 C57BL/6J ±  kb
transcript OTTMUST00000149215 VEGA | MGI Sequence Detail 3934 Not Applicable  
polypeptide OTTMUSP00000077448 VEGA | MGI Sequence Detail 610 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    185 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000014751 splicing factor, arginine/serine-rich 12
  • InterPro Domains
    IPR012677 Nucleotide-binding alpha-beta plait domain
    IPR000504 RNA recognition motif domain
    IPR033568 Splicing regulatory glutamine/lysine-rich protein 1
Molecular
Reagents
less
  • All nucleic 19
    cDNA 18
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
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MGI:2145251, MGI:3034554
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory