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Lhfpl2 Gene Detail
Summary
  • Symbol
    Lhfpl2
  • Name
    lipoma HMGIC fusion partner-like 2
  • Synonyms
    mKIAA0206, vgim
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145236
    NCBI Gene: 218454
  • Gene Overview
    MyGene.info: LHFPL2
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr13:94057796-94195409 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      137614 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 49.03 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    LHFPL2, LHFPL tetraspan subfamily member 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LHFPL2, LHFPL tetraspan subfamily member 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 10184
    neXtProt AC: NX_Q6ZUX7
    UniProt: Q6ZUX7

  • Chr Location
    5q14.1; chr5:78485215-78648895 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    22 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Females homozygous for a spontaneous point mutation have a completely closed vagina, soft swelling of the perineum and buildup of viscous fluid in the uteri.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
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    Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000027714 VEGA Gene Model | MGI Sequence Detail 137614 C57BL/6J ±  kb
    transcript OTTMUST00000068582 VEGA | MGI Sequence Detail 4348 Not Applicable  
    polypeptide OTTMUSP00000034709 VEGA | MGI Sequence Detail 222 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      1094 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 13
      Primer pair 2

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:2145409, MGI:4837107
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 13
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:259848 Chal J, et al., Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro. Development. 2018 Mar 19;145(6)

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    06/12/2018
    MGI 6.12
    The Jackson Laboratory