About   Help   FAQ
Lhfpl2
Gene Detail
Symbol

Name
ID
Lhfpl2
lipoma HMGIC fusion partner-like 2
MGI:2145236
Synonyms
mKIAA0206, vgim
Feature Type
protein coding gene
Genetic Map
Chromosome 13
49.03 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:94057796-94195409 bp, + strand
From VEGA annotation of GRCm38

  137614 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4222  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: LHFPL2
Protein SuperFamily: Lipoma HMGIC fusion partner precursor
Gene Tree: Lhfpl2

Human
homologs
LHFPL2, lipoma HMGIC fusion partner-like 2
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10184
neXtProt AC: NX_Q6ZUX7

Human Chr (Location): 5q14.1; chr5:78485215-78648895 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Spontaneous(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Females homozygous for a spontaneous point mutation have a completely closed vagina, soft swelling of the perineum and buildup of viscous fluid in the uteri.
 
Interactions
Lhfpl2 interacts with 326 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process biological_process
Component integral component of membrane, membrane
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(10)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase lhfpl2 ; ZFIN lhfpl2a, lhfpl2b    NEW 
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000027714 (Evidence)
Ensembl Gene Model ENSMUSG00000045312 (Evidence)
Entrez Gene 218454 (Evidence)
DFCI TC1581372, TC1601458, TC1613815, TC1637199, TC1716242
DoTS DT.101737647, DT.40135636, DT.531661, DT.55115168, DT.91573918
NIA Mouse Gene Index U015126
Consensus CDS Project CCDS26692.1
International Mouse Phenotyping Consortium Status Lhfpl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027714 VEGA Gene Model | MGI Sequence Detail 137614 C57BL/6J ±  kb
transcript OTTMUST00000068582 VEGA | MGI Sequence Detail 4348 Not Applicable 
polypeptide OTTMUSP00000034709 VEGA | MGI Sequence Detail 222 Not Applicable 

For the selected sequences
All sequences(82) RefSeq(20) UniProt(3)
Polymorphisms
SNPs within 2kb(1096 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR019372 Lipoma HMGIC fusion partner-like protein
Protein Ontology PR:000009786 lipoma HMGIC fusion partner-like 2 protein
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:222308 Fairfield H, et al., Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders. Genome Res. 2015 Jul;25(7):948-57
All references(33)
Other
accession IDs
MGI:2145409, MGI:4837107

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/18/2015
MGI 6.0
The Jackson Laboratory