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Lhfpl2 Gene Detail
Summary
  • Symbol
    Lhfpl2
  • Name
    lipoma HMGIC fusion partner-like 2
  • Synonyms
    mKIAA0206, vgim
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145236
    NCBI Gene: 218454
  • Gene Overview
    MyGene.info: LHFPL2
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr13:94057796-94195409 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      137614 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 49.03 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    LHFPL2, LHFPL tetraspan subfamily member 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LHFPL2, LHFPL tetraspan subfamily member 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 10184
    neXtProt AC: NX_Q6ZUX7
    UniProt: Q6ZUX7

  • Chr Location
    5q14.1; chr5:78485215-78648895 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    22 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Females homozygous for a spontaneous point mutation have a completely closed vagina, soft swelling of the perineum and buildup of viscous fluid in the uteri.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027714 VEGA Gene Model | MGI Sequence Detail 137614 C57BL/6J ±  kb
transcript OTTMUST00000068582 VEGA | MGI Sequence Detail 4348 Not Applicable  
polypeptide OTTMUSP00000034709 VEGA | MGI Sequence Detail 222 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1094 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 12
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
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MGI:2145409, MGI:4837107
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 13
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:241136 Zhao F, et al., Novel function of LHFPL2 in female and male distal reproductive tract development. Sci Rep. 2016 Mar 11;6:23037

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory