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Cog5 Gene Detail
Summary
  • Symbol
    Cog5
  • Name
    component of oligomeric golgi complex 5
  • Synonyms
    5430405C01Rik, GOLTC1, GTC90
  • Feature Type
    protein coding gene
  • IDs
    MGI:2145130
    NCBI Gene: 238123
  • Gene Overview
    MyGene.info: COG5
Location & Maps
more
  • Sequence Map
    Chr12:31654869-31937630 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      282762 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 13.68 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    COG5, component of oligomeric golgi complex 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    COG5, component of oligomeric golgi complex 5
    Orthology source: HomoloGene
  • Synonyms
    CDG2I, GOLTC1, GTC90
  • Links
    NCBI Gene ID: 10466
    neXtProt AC: NX_Q9UP83

  • Chr Location
    7q31; chr7:107201744-107564514 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 42221
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: COG5
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human COG5 associations

Human Disease Mouse Models
       Congenital Disorder of Glycosylation, Type III; CDG2I   OMIM: 613612
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035933 Ensembl Gene Model | MGI Sequence Detail 282762 C57BL/6J ±  kb
transcript ENSMUST00000036862 Ensembl | MGI Sequence Detail 2997 Not Applicable  
polypeptide ENSMUSP00000044797 Ensembl | MGI Sequence Detail 829 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1212 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000005688 conserved oligomeric Golgi complex subunit 5
  • InterPro Domains
    IPR019465 Conserved oligomeric Golgi complex subunit 5
Molecular
Reagents
less
  • All nucleic 57
    cDNA 57

    Microarray probesets 6
Other
Accession IDs
less
MGI:2145129
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory