Eif2b2
Gene Detail

Symbol Name ID

Eif2b2 eukaryotic translation initiation factor 2B, subunit 2 beta MGI:2145118

Synonyms

EIF2B, EIF-2Bbeta

Feature Type

protein coding gene

Genetic Map

Chromosome 12

39.60 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr12:85219481-85226628 bp, + strand From VEGA annotation of GRCm38   7148 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:6507  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Eif2b2

Human homologs

Human Homolog		EIF2B2, eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
NCBI Gene ID		8892
neXtProt AC		NX_P49770
Human Synonyms		EIF2B, EIF-2Bbeta
Human Chr (Location)		14q24.3; chr14:75469612-75476294 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human EIF2B2

Alleles and phenotypes

All alleles(4) : Targeted(2) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (25 annotations)

Process	cellular metabolic process, cellular response to stimulus, ...
Component	cytoplasm, eukaryotic translation initiation factor 2B complex
Function	ATP binding, GTP binding, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (46)    Tissues (31)    Images (8)
Theiler Stages: 2, 3, 4, 5, 23, 28

Assay Type	Results
RNA in situ	31
RT-PCR	15

cDNA source data(95)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(96) cDNA(95) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000030645 (Evidence)
Ensembl Gene Model	ENSMUSG00000004788 (Evidence)
Entrez Gene	217715 (Evidence)
UniGene	29041
DFCI	TC1572512, TC1775836
DoTS	DT.493601, DT.94216341
NIA Mouse Gene Index	U014207
Consensus CDS Project	CCDS26053.1
International Mouse Knockout Project Status	Eif2b2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000030645	VEGA Gene Model | MGI Sequence Detail	7148	C57BL/6J
transcript	OTTMUST00000075867	VEGA | MGI Sequence Detail	1605	Not Applicable
polypeptide	OTTMUSP00000039844	VEGA | MGI Sequence Detail	351	Not Applicable

All sequences(51) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(10 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000649	Initiation factor 2B-related
Protein Ontology	PR:000006963	translation initiation factor eIF-2B subunit beta

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)

Other accession IDs

MGI:2144728