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Adi1 Gene Detail
Summary
  • Symbol
    Adi1
  • Name
    acireductone dioxygenase 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144929
    NCBI Gene: 104923
  • Gene Overview
    MyGene.info: ADI1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:28675231-28682175 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 11.05 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    190 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144929
protein coding gene Chr12:28675207-28682175 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019645
protein coding gene Chr12:26512785-26521105 (+)
A/J MGP_AJ_G0019612
protein coding gene Chr12:25799349-25806892 (+)
AKR/J MGP_AKRJ_G0019583
protein coding gene Chr12:26660378-26670903 (+)
BALB/cJ MGP_BALBcJ_G0019589
protein coding gene Chr12:26050926-26058096 (+)
C3H/HeJ MGP_C3HHeJ_G0019393
protein coding gene Chr12:26520835-26527611 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020036
protein coding gene Chr12:27368291-27375172 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017661
protein coding gene Chr12:25155510-25162533 (+)
CAST/EiJ MGP_CASTEiJ_G0018948
protein coding gene Chr12:21482924-21489565 (+)
CBA/J MGP_CBAJ_G0019364
protein coding gene Chr12:28330848-28337687 (+)
DBA/2J MGP_DBA2J_G0019478
protein coding gene Chr12:25652527-25660295 (+)
FVB/NJ MGP_FVBNJ_G0019469
protein coding gene Chr12:25452403-25459418 (+)
LP/J MGP_LPJ_G0019548
protein coding gene Chr12:26599490-26606466 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019504
protein coding gene Chr12:27963021-27972761 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020076
protein coding gene Chr12:26178368-26185328 (+)
PWK/PhJ MGP_PWKPhJ_G0018715
protein coding gene Chr12:20357437-20364330 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018503
protein coding gene Chr12:20762506-20769399 (+)
WSB/EiJ MGP_WSBEiJ_G0018999
protein coding gene Chr12:26381028-26387979 (+)



Homology
more
  • Human Ortholog
    ADI1, acireductone dioxygenase 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ADI1, acireductone dioxygenase 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    APL1, ARD, Fe-ARD, HMFT1638, MTCBP1, mtnD, Ni-ARD, SIPL
  • Links
    NCBI Gene ID: 55256
    neXtProt AC: NX_Q9BV57
    UniProt: Q9BV57

  • Chr Location
    2p25.3; chr2:3497919-3519579 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 75081
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;2 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ADI1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020629 Ensembl Gene Model | MGI Sequence Detail 6945 C57BL/6J ±  kb
transcript ENSMUST00000020957 Ensembl | MGI Sequence Detail 1652 Not Applicable  
polypeptide ENSMUSP00000020957 Ensembl | MGI Sequence Detail 179 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 99
    cDNA 99

    Microarray probesets 2
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory