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Tmem11 Gene Detail
Summary
  • Symbol
    Tmem11
  • Name
    transmembrane protein 11
  • Synonyms
    5730466P16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144726
    NCBI Gene: 216821
Location & Maps
more
  • Sequence Map
    Chr11:60864452-60879272 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14821 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 37.90 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TMEM11, transmembrane protein 11
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMEM11, transmembrane protein 11
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C17orf35, PM1, PMI
  • Links
    NCBI Gene ID: 8834
    neXtProt AC: NX_P17152

  • Chr Location
    17p11.2; chr17:21197950-21214595 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 2879
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: TMEM11
  • Gene Tree
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    24 phenotype references
  • All Mutations and Alleles
    35
  • Chemically induced (other)
    1
  • Gene trapped
    30
  • Targeted
    4
  • Genomic Mutations
    3 involving Tmem11
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007749 VEGA Gene Model | MGI Sequence Detail 14821 C57BL/6J ±  kb
transcript OTTMUST00000017713 VEGA | MGI Sequence Detail 1457 Not Applicable  
polypeptide OTTMUSP00000008168 VEGA | MGI Sequence Detail 190 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    149 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000031412 transmembrane protein 11, mitochondrial
  • InterPro Domains
    IPR026120 Transmembrane protein 11
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Diseases 2
    Gene Ontology 3
    Phenotypes 24
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:198500 Nakahara M, et al., Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. Mamm Genome. 2013 Jun;24(5-6):228-39

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory