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Ttc7b Gene Detail
Summary
  • Symbol
    Ttc7b
  • Name
    tetratricopeptide repeat domain 7B
  • Synonyms
    Ttc7l1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144724
    NCBI Gene: 104718
Location & Maps
more
  • Sequence Map
    Chr12:100300771-100520822 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      220052 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 50.43 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TTC7B, tetratricopeptide repeat domain 7B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TTC7B, tetratricopeptide repeat domain 7B
    Orthology source: HomoloGene
  • Synonyms
    c14_5685, TTC7L1
  • Links
    NCBI Gene ID: 145567
    neXtProt AC: NX_Q86TV6

  • Chr Location
    14q32.11; chr14:90540588-90816479 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 14675
    1 human;1 mouse;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: TTC7B
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    17
  • Chemically induced (other)
    1
  • Gene trapped
    14
  • Targeted
    2
  • Genomic Mutations
    1 involving Ttc7b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033530 Ensembl Gene Model | MGI Sequence Detail 220052 C57BL/6J ±  kb
transcript ENSMUST00000062957 Ensembl | MGI Sequence Detail 3441 Not Applicable  
polypeptide ENSMUSP00000052107 Ensembl | MGI Sequence Detail 843 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1506 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000029840 tetratricopeptide repeat protein 7B
  • InterPro Domains
    IPR011990 Tetratricopeptide-like helical domain
    IPR019734 Tetratricopeptide repeat
    IPR013105 Tetratricopeptide repeat 2
    IPR013026 Tetratricopeptide repeat-containing domain
Molecular
Reagents
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  • All nucleic 56
    Genomic 1
    cDNA 55

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory