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Tubg2 Gene Detail
Summary
  • Symbol
    Tubg2
  • Name
    tubulin, gamma 2
  • Synonyms
    Tubgl
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144208
    NCBI Gene: 103768
  • Gene Overview
    MyGene.info: TUBG2
Location & Maps
more
  • Sequence Map
    Chr11:101155907-101161787 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5881 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 64.30 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TUBG2, tubulin gamma 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TUBG2, tubulin gamma 2
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 27175
    neXtProt AC: NX_Q9NRH3

  • Chr Location
    17q21.2; chr17:42659248-42667006 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    1
  • Targeted
    4
  • Genomic Mutations
    1 involving Tubg2
  • Incidental Mutations
    APF
Homozygous null mice are viable and fertile with normal weight and no significant histological abnormalities in the brain or other tissues.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002705 VEGA Gene Model | MGI Sequence Detail 5881 C57BL/6J ±  kb
transcript OTTMUST00000005343 VEGA | MGI Sequence Detail 1754 Not Applicable  
polypeptide OTTMUSP00000002533 VEGA | MGI Sequence Detail 451 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    55 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
Other
Accession IDs
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MGI:1930396
References
more
  • Summaries
    All 93
    Developmental Gene Expression 59
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:65084 Pershouse M, et al., BAC contig from a 3-cM region of mouse chromosome 11 surrounding brca1. Genomics. 2000 Oct 1;69(1):139-42
  • Latest
    J:232342 Stewart K, et al., A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects. PLoS Genet. 2016 Feb;12(2):e1005785

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory