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Mief2 Gene Detail
Summary
  • Symbol
    Mief2
  • Name
    mitochondrial elongation factor 2
  • Synonyms
    LOC237781, Smcr7
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144199
    NCBI Gene: 237781
Location & Maps
more
  • Sequence Map
    Chr11:60728398-60732951 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4554 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 37.81 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    MIEF2, mitochondrial elongation factor 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MIEF2, mitochondrial elongation factor 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MID49, SMCR7
  • Links
    NCBI Gene ID: 125170
    neXtProt AC: NX_Q96C03

  • Chr Location
    17p11.2; chr17:18260534-18265781 (+)  GRCh38.p2

Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    17 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Targeted
    5
  • Genomic Mutations
    3 involving Mief2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007763 VEGA Gene Model | MGI Sequence Detail 4554 C57BL/6J ±  kb
transcript OTTMUST00000017730 VEGA | MGI Sequence Detail 2522 Not Applicable  
polypeptide OTTMUSP00000008171 VEGA | MGI Sequence Detail 454 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    42 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000015278 Smith-Magenis syndrome chromosome region candidate gene 7 protein
  • PDB
  • InterPro Domains
    IPR024810 Mab-21 domain
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
Other
Accession IDs
less
MGI:2684857
References
more
  • Summaries
    All 28
    Diseases 2
    Gene Ontology 3
    Phenotypes 17
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:208253 Richter V, et al., Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission. J Cell Biol. 2014 Feb 17;204(4):477-86

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory