About   Help   FAQ
Nup107 Gene Detail
Summary
  • Symbol
    Nup107
  • Name
    nucleoporin 107
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143854
    NCBI Gene: 103468
  • Gene Overview
    MyGene.info: NUP107
Location & Maps
more
  • Sequence Map
    Chr10:117750624-117792705 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      42082 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 66.32 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    NUP107, nucleoporin 107
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NUP107, nucleoporin 107
    Orthology source: HomoloGene
  • Synonyms
    NPHS11, NUP84
  • Links
    NCBI Gene ID: 57122
    neXtProt AC: NX_P57740

  • Chr Location
    12q15; chr12:68686951-68742693 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 5555
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: NUP107
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human NUP107 associations

Human Disease Mouse Models
       Nephrotic Syndrome, Type 11; NPHS11   OMIM: 616730
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    19
  • Chemically induced (other)
    1
  • Gene trapped
    18
  • Genomic Mutations
    1 involving Nup107
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000052798 Ensembl Gene Model | MGI Sequence Detail 42082 C57BL/6J ±  kb
transcript ENSMUST00000064848 Ensembl | MGI Sequence Detail 3092 Not Applicable  
polypeptide ENSMUSP00000063590 Ensembl | MGI Sequence Detail 926 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    366 from dbSNP Build 142
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000011506 nuclear pore complex protein Nup107
  • InterPro Domains
    IPR007252 Nuclear pore protein 84/107
Molecular
Reagents
less
  • All nucleic 104
    cDNA 104

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143913
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:160544 Kim CE, et al., A molecular mechanism underlying the neural-specific defect in torsinA mutant mice. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9861-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/23/2016
MGI 6.05
The Jackson Laboratory