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Zfp365 Gene Detail
Summary
  • Symbol
    Zfp365
  • Name
    zinc finger protein 365
  • Synonyms
    DBZ, mKIAA0844, Su48
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143676
    NCBI Gene: 216049
  • Gene Overview
    MyGene.info: ZNF365
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:67886105-67912662 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 35.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    425 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143676
protein coding gene Chr10:67886103-67912662 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017327
protein coding gene Chr10:67675532-67702040 (-)
A/J MGP_AJ_G0017304
protein coding gene Chr10:65404289-65430820 (-)
AKR/J MGP_AKRJ_G0017265
protein coding gene Chr10:67187270-67214243 (-)
BALB/cJ MGP_BALBcJ_G0017264
protein coding gene Chr10:65612876-65639415 (-)
C3H/HeJ MGP_C3HHeJ_G0017088
protein coding gene Chr10:67188041-67214617 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017722
protein coding gene Chr10:70107419-70135782 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015412
protein coding gene Chr10:62090621-62117380 (-)
CAST/EiJ MGP_CASTEiJ_G0016658
protein coding gene Chr10:67244965-67271622 (-)
CBA/J MGP_CBAJ_G0017060
protein coding gene Chr10:72786485-72813044 (-)
DBA/2J MGP_DBA2J_G0017165
protein coding gene Chr10:64787811-64814285 (-)
FVB/NJ MGP_FVBNJ_G0017158
protein coding gene Chr10:63946901-63976560 (-)
LP/J MGP_LPJ_G0017238
protein coding gene Chr10:68086396-68117254 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017186
protein coding gene Chr10:74985102-75014170 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017761
protein coding gene Chr10:67085629-67112197 (-)
PWK/PhJ MGP_PWKPhJ_G0016442
protein coding gene Chr10:64590362-64617445 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016224
protein coding gene Chr10:66464628-66493304 (-)
WSB/EiJ MGP_WSBEiJ_G0016722
protein coding gene Chr10:67026315-67053731 (-)



Homology
more
  • Human Ortholog
    ZNF365, zinc finger protein 365
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ZNF365, zinc finger protein 365
    Orthology source: HGNC, HomoloGene
  • Synonyms
    Su48, UAN, ZNF365D
  • Links
    NCBI Gene ID: 22891
    neXtProt AC: NX_Q70YC4, NX_Q70YC5
    UniProt: Q70YC4, Q70YC5

  • Chr Location
    10q21.2; chr10:62373609-62672011 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ZNF365 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit abnormal cortical basket cells in the somatosensory cortices, delayed myelination in the corpus callosum during the early postnatal period, and an increase in immature oligodendrocytes.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 216049 NCBI Gene Model | MGI Sequence Detail 26558 C57BL/6J ±  kb
    transcript NM_178679 RefSeq | MGI Sequence Detail 4279 C57BL/6  
    polypeptide Q8BG89 UniProt | EBI | MGI Sequence Detail 408 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 43
      cDNA 40
      Primer pair 3

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2143789
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 6
      Gene Ontology 8
      Phenotypes 16
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:243476 Koyama Y, et al., Alterations in dendrite and spine morphology of cortical pyramidal neurons in DISC1-binding zinc finger protein (DBZ) knockout mice. Front Neuroanat. 2015;9:52

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    12/11/2018
    MGI 6.13
    The Jackson Laboratory