About   Help   FAQ
Mfsd4b1 Gene Detail
Summary
  • Symbol
    Mfsd4b1
  • Name
    major facilitator superfamily domain containing 4B1
  • Synonyms
    AI317395
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143575
    NCBI Gene: 215929
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:39877571-39901264 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 21.43 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1387 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143575
 protein coding gene Chr10:39877569-39901264 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017158
 protein coding gene Chr10:38546589-38569032 (-)
A/J MGP_AJ_G0017135
 protein coding gene Chr10:37504668-37529935 (-)
AKR/J MGP_AKRJ_G0017095
 protein coding gene Chr10:38036488-38063073 (-)
BALB/cJ MGP_BALBcJ_G0017098
 protein coding gene Chr10:37574062-37600628 (-)
C3H/HeJ MGP_C3HHeJ_G0016918
 protein coding gene Chr10:38357471-38385242 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017556
 protein coding gene Chr10:39724080-39753287 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015252
 protein coding gene Chr10:35489328-35509496 (-)
CAST/EiJ MGP_CASTEiJ_G0016497
 protein coding gene Chr10:38537574-38563340 (-)
CBA/J MGP_CBAJ_G0016892
 protein coding gene Chr10:41551970-41580136 (-)
DBA/2J MGP_DBA2J_G0016997
 protein coding gene Chr10:37023160-37047643 (-)
FVB/NJ MGP_FVBNJ_G0016992
 protein coding gene Chr10:36529232-36552734 (-)
LP/J MGP_LPJ_G0017074
 protein coding gene Chr10:38512769-38536454 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017022
 protein coding gene Chr10:42391716-42416335 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017593
 protein coding gene Chr10:38024036-38048816 (-)
PWK/PhJ MGP_PWKPhJ_G0016277
 protein coding gene Chr10:36884506-36908410 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016061
 protein coding gene Chr10:37841021-37868041 (-)
WSB/EiJ MGP_WSBEiJ_G0016560
 protein coding gene Chr10:38308166-38333258 (-)



Homology
more
  • Human Ortholog
    MFSD4B, major facilitator superfamily domain containing 4B
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MFSD4B, major facilitator superfamily domain containing 4B
  • Synonyms
    KIAA1919, NaGLT1, SLC60A2
  • Links
    NCBI Gene ID: 91749
    UniProt: Q5TF39

  • Chr Location
    6q21; chr6:111259327-111445354 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Mfsd4b1
  • Find Mice (IMSR)
    22 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    875
  • Tissues
    157
  • cDNA Data
    8
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038522 Ensembl Gene Model | MGI Sequence Detail 23694 C57BL/6J ±  kb
transcript ENSMUST00000163705 Ensembl | MGI Sequence Detail 2677 Not Applicable  
polypeptide ENSMUSP00000128324 Ensembl | MGI Sequence Detail 425 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 6
Other
Accession IDs
less
MGI:2143629
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Phenotypes 9
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory