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Rdh9 Gene Detail
Summary
  • Symbol
    Rdh9
  • Name
    retinol dehydrogenase 9
  • Synonyms
    Crad3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143528
    NCBI Gene: 103142
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:127612274-127628566 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 75.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    60 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143528
 protein coding gene Chr10:127612255-127628566 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017837
 protein coding gene Chr10:131411873-131448952 (+)
A/J MGP_AJ_G0017811
 protein coding gene Chr10:126151859-126153302 (+)
AKR/J MGP_AKRJ_G0017775
 protein coding gene Chr10:129873413-129906755 (+)
BALB/cJ MGP_BALBcJ_G0017776
 protein coding gene Chr10:126550633-126566365 (+)
C3H/HeJ MGP_C3HHeJ_G0017599
 protein coding gene Chr10:130025683-130027659 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018231
 protein coding gene Chr10:135863610-135876056 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0017159
 protein coding gene Chr10:130749102-130765724 (+)
CBA/J MGP_CBAJ_G0017569
 protein coding gene Chr10:141344740-141372711 (+)
DBA/2J MGP_DBA2J_G0017675
 protein coding gene Chr10:125223733-125240853 (+)
FVB/NJ MGP_FVBNJ_G0017670
 protein coding gene Chr10:124170574-124185096 (+)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0018271
 protein coding gene Chr10:129950682-129969888 (+)
PWK/PhJ MGP_PWKPhJ_G0016945
 protein coding gene Chr10:125450855-125494695 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0017219
 protein coding gene Chr10:130153853-130230775 (+)



Homology
more
  • Human Ortholog
    RDH16, retinol dehydrogenase 16
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RDH16, retinol dehydrogenase 16
  • Synonyms
    hRDH-E, RODH4, RODH-4, SDR9C8
  • Links
    NCBI Gene ID: 8608
    neXtProt AC: NX_O75452
    UniProt: O75452

  • Chr Location
    12q13.3; chr12:56951431-56959374 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Mice homozygous for a knock-out allele are viable, fertile and healthy, with no apparent alterations in tissue retinoid and serum dihydrotestosterone levels.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    9
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 103142 NCBI Gene Model | MGI Sequence Detail 16293 C57BL/6J ±  kb
transcript NM_153133 RefSeq | MGI Sequence Detail 2698 C57BL/6  
polypeptide NP_694773 RefSeq | MGI Sequence Detail 317 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR036291 NAD(P)-binding domain superfamily
    IPR020904 Short-chain dehydrogenase/reductase, conserved site
    IPR002347 Short-chain dehydrogenase/reductase SDR
Molecular
Reagents
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  • All nucleic 10
    cDNA 9
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 25
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:83534 Zhuang R, et al., cis-Retinol/androgen dehydrogenase, isozyme 3 (CRAD3): a short-chain dehydrogenase active in a reconstituted path of 9-cis-retinoic acid biosynthesis in intact cells. Biochemistry. 2002 Mar 12;41(10):3477-83
  • Latest
    J:259735 Rocha AS, et al., The Angiocrine Factor Rspondin3 Is a Key Determinant of Liver Zonation. Cell Rep. 2015 Dec 1;13(9):1757-64
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory