Rdh9
Gene Detail

Symbol Name ID

Rdh9 retinol dehydrogenase 9 MGI:2143528

Synonyms

Crad3

Feature Type

protein coding gene

Genetic Map

Chromosome 10

75.21 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr10:127759787-127792697 bp, + strand From VEGA annotation of GRCm38   32911 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:74505  Vertebrate Homology Class
5 mouse; 1 rat; 1 zebrafish

Protein SuperFamily: retinol dehydrogenase
Gene Tree: Rdh9

Alleles and phenotypes

All alleles(3) : Targeted(3)
 

Mice homozygous for a knock-out allele are viable, fertile and healthy, with no apparent alterations in tissue retinoid and serum dihydrotestosterone levels.

 

Gene Ontology (GO) classifications

All GO classifications: (4 annotations)

Process	9-cis-retinoic acid biosynthetic process, oxidation-reduction process
Component	cellular_component
Function	retinol dehydrogenase activity

External Resources: FuncBase

Expression

Literature Summary: (2 records)
cDNA source data(8)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(8) cDNA(8)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000027659 (Evidence)
Ensembl Gene Model	ENSMUSG00000056148 (Evidence)
Entrez Gene	103142 (Evidence)
UniGene	235814
DFCI	TC1588203, TC1596822
DoTS	DT.110592362, DT.87060812, DT.94338687
NIA Mouse Gene Index	U012163
Consensus CDS Project	CCDS24251.1
International Mouse Knockout Project Status	Rdh9

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027659	VEGA Gene Model | MGI Sequence Detail	32911	C57BL/6J
transcript	OTTMUST00000068438	VEGA | MGI Sequence Detail	2698	Not Applicable
polypeptide	OTTMUSP00000034607	VEGA | MGI Sequence Detail	317	Not Applicable

All sequences(39) RefSeq(2) UniProt(5)

Polymorphisms

SNPs(56 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002347	Glucose/ribitol dehydrogenase
InterPro	IPR016040	NAD(P)-binding domain
InterPro	IPR020904	Short-chain dehydrogenase/reductase, conserved site
InterPro	IPR002198	Short-chain dehydrogenase/reductase SDR

References

(Earliest) J:83534 Zhuang R, et al., cis-Retinol/androgen dehydrogenase, isozyme 3 (CRAD3): a short-chain dehydrogenase active in a reconstituted path of 9-cis-retinoic acid biosynthesis in intact cells. Biochemistry. 2002 Mar 12;41(10):3477-83
(Latest) J:177585 Hesse K, et al., AP-2delta is a crucial transcriptional regulator of the posterior midbrain. PLoS One. 2011;6(8):e23483
All references(24)