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Slc6a15
Gene Detail
 Symbol
Name
ID
Slc6a15
solute carrier family 6 (neurotransmitter transporter), member 15
MGI:2143484
Synonyms v7-3
Feature Type protein coding gene
Genetic Map
Chromosome 10
53.98 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:103367808-103419378 bp, + strand
From Ensembl annotation of GRCm38

  51571 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18163  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Slc6a15

Human
homologs
Human Homolog SLC6A15, solute carrier family 6 (neutral amino acid transporter), member 15
NCBI Gene ID 55117
neXtProt AC  NX_Q9H2J7
Human Synonyms  hv7-3, NTT73, SBAT1, V7-3
Human Chr (Location)  12q21.3; chr12:84859488-84912829 (-)  GRCh38
Alleles
and
phenotypes
All alleles(6) : Gene trapped(2) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit decreased synaptosome transport activities but exhibit no behavioral abnormalities.
 
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process amino acid transport, ion transport, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function neurotransmitter:sodium symporter activity, proline:sodium symporter activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (268)    Tissues (82)    Images (49)
Theiler Stages: 22, 23, 24, 26, 28
Assay TypeResults
RNA in situ 268
cDNA source data(38)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(41) cDNA(40) Primer pair(1)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000019894 (Evidence)
Entrez Gene103098 (Evidence)
UniGene458408
DFCITC1577905, TC1595871, TC1636810
DoTSDT.101735936, DT.40176071, DT.94143404, DT.94266531
NIA Mouse Gene IndexU011977
Consensus CDS ProjectCCDS24156.1
International Mouse Knockout Project StatusSlc6a15
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019894 Ensembl Gene Model | MGI Sequence Detail 51571 C57BL/6J ±  kb
transcript ENSMUST00000074204 Ensembl | MGI Sequence Detail 3643 Not Applicable 
polypeptide ENSMUSP00000073829 Ensembl | MGI Sequence Detail 729 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(10) UniProt(3)
Polymorphisms SNPs within 2kb(465 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000175 Sodium:neurotransmitter symporter
InterPro IPR002438 Sodium:neurotransmitter symporter, orphan
Protein Ontology PR:000015181 sodium-dependent neutral amino acid transporter B(0)AT2
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:206404 Drgonova J, et al., Involvement of the neutral amino acid transporter SLC6A15 and leucine in obesity-related phenotypes. PLoS One. 2013;8(9):e68245
All references(39)
Other
accession IDs
MGI:2143583, MGI:2143584

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory