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Exog Gene Detail
Summary
  • Symbol
    Exog
  • Name
    endo/exonuclease (5'-3'), endonuclease G-like
  • Synonyms
    Endogl1, ENDOGL2, ENGL-a, ENGL-B
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143333
    NCBI Gene: 208194
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:119444943-119465517 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 71.33 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    166 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143333
protein coding gene Chr9:119444923-119465518 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035420
protein coding gene Chr9:122221119-122246452 (+)
A/J MGP_AJ_G0035401
protein coding gene Chr9:117667149-117687513 (+)
AKR/J MGP_AKRJ_G0035334
protein coding gene Chr9:120739271-120762254 (+)
BALB/cJ MGP_BALBcJ_G0035397
protein coding gene Chr9:117545772-117567066 (+)
C3H/HeJ MGP_C3HHeJ_G0035105
protein coding gene Chr9:121201097-121225114 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035920
protein coding gene Chr9:125551758-125578388 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032802
protein coding gene Chr9:114866861-114888605 (+)
CAST/EiJ MGP_CASTEiJ_G0034408
protein coding gene Chr9:121189915-121214172 (+)
CBA/J MGP_CBAJ_G0035072
protein coding gene Chr9:130265683-130295344 (+)
DBA/2J MGP_DBA2J_G0035231
protein coding gene Chr9:117109326-117131259 (+)
FVB/NJ MGP_FVBNJ_G0035178
protein coding gene Chr9:115968762-115990054 (+)
LP/J MGP_LPJ_G0035310
protein coding gene Chr9:122562309-122581992 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035219
protein coding gene Chr9:131232034-131257911 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035939
protein coding gene Chr9:121122438-121145367 (+)
PWK/PhJ MGP_PWKPhJ_G0034114
protein coding gene Chr9:117541075-117562762 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033950
protein coding gene Chr9:121226706-121248183 (+)
WSB/EiJ MGP_WSBEiJ_G0034529
protein coding gene Chr9:121006904-121029093 (+)



Homology
more
  • Human Ortholog
    EXOG, exo/endonuclease G
  • Vertebrate Orthologs
    8
  • Human Ortholog
    EXOG, exo/endonuclease G
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ENDOGL1, ENDOGL2, ENGL, ENGL-a, ENGLA, ENGL-b, ENGLB
  • Links
    NCBI Gene ID: 9941
    neXtProt AC: NX_Q9Y2C4
    UniProt: Q9Y2C4

  • Chr Location
    3p22.2; chr3:38496127-38526305 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042787 Ensembl Gene Model | MGI Sequence Detail 20575 C57BL/6J ±  kb
transcript ENSMUST00000035094 Ensembl | MGI Sequence Detail 3832 Not Applicable  
polypeptide ENSMUSP00000035094 Ensembl | MGI Sequence Detail 368 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 52

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:91812 Stryke D, et al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 2003 Jan 1;31(1):278-81
  • Latest
    J:218220 Szczesny B, et al., Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function. Nucleic Acids Res. 2014 Dec 1;42(21):13161-73

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory