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Klhl18 Gene Detail
Summary
  • Symbol
    Klhl18
  • Name
    kelch-like 18
  • Synonyms
    MGC:36415
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143315
    NCBI Gene: 270201
  • Gene Overview
    MyGene.info: KLHL18
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:110425926-110476694 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    146 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143315
protein coding gene Chr9:110425926-110476694 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035348
protein coding gene Chr9:112572695-112633673 (-)
A/J MGP_AJ_G0035329
protein coding gene Chr9:108483857-108535806 (-)
AKR/J MGP_AKRJ_G0035260
protein coding gene Chr9:111178961-111233627 (-)
BALB/cJ MGP_BALBcJ_G0035324
protein coding gene Chr9:108231441-108281196 (-)
C3H/HeJ MGP_C3HHeJ_G0035032
protein coding gene Chr9:111685217-111741046 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035846
protein coding gene Chr9:115628946-115685694 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032732
protein coding gene Chr9:105705353-105755926 (-)
CAST/EiJ MGP_CASTEiJ_G0034337
protein coding gene Chr9:111460290-111522501 (-)
CBA/J MGP_CBAJ_G0034999
protein coding gene Chr9:119935035-119996651 (-)
DBA/2J MGP_DBA2J_G0035158
protein coding gene Chr9:107950446-107998280 (-)
FVB/NJ MGP_FVBNJ_G0035105
protein coding gene Chr9:106772767-106824470 (-)
LP/J MGP_LPJ_G0035237
protein coding gene Chr9:112873190-112926597 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035145
protein coding gene Chr9:121291377-121341078 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035866
protein coding gene Chr9:111509817-111562622 (-)
PWK/PhJ MGP_PWKPhJ_G0034045
protein coding gene Chr9:108189555-108241794 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033880
protein coding gene Chr9:111597332-111651256 (-)
WSB/EiJ MGP_WSBEiJ_G0034459
protein coding gene Chr9:111382836-111432609 (-)



Homology
more
  • Human Ortholog
    KLHL18, kelch like family member 18
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KLHL18, kelch like family member 18
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 23276
    neXtProt AC: NX_O94889
    UniProt: O94889

  • Chr Location
    3p21.31; chr3:47282840-47346816 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 270201 NCBI Gene Model | MGI Sequence Detail 50769 C57BL/6J ±  kb
transcript NM_001360306 RefSeq | MGI Sequence Detail 4588 C57BL/6  
polypeptide NP_001347235 RefSeq | MGI Sequence Detail 579 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    cDNA 57

    Microarray probesets 4
References
more
  • Summaries
    All 22
    Developmental Gene Expression 2
    Phenotypes 4
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory