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Phldb1 Gene Detail
Summary
  • Symbol
    Phldb1
  • Name
    pleckstrin homology like domain, family B, member 1
  • Synonyms
    D330037A14Rik, LL5A, mKIAA0638
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143230
    NCBI Gene: 102693
  • Gene Overview
    MyGene.info: PHLDB1
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:44686304-44735198 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 24.84 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    463 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143230
 protein coding gene Chr9:44686304-44735248 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034716
 protein coding gene Chr9:43210411-43259188 (-)
A/J MGP_AJ_G0034697
 protein coding gene Chr9:41989775-42040997 (-)
AKR/J MGP_AKRJ_G0034624
 protein coding gene Chr9:42863796-42912960 (-)
BALB/cJ MGP_BALBcJ_G0034688
 protein coding gene Chr9:41736289-41785146 (-)
C3H/HeJ MGP_C3HHeJ_G0034399
 protein coding gene Chr9:43316947-43366819 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035209
 protein coding gene Chr9:44485055-44537513 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032124
 protein coding gene Chr9:41560917-41610583 (-)
CAST/EiJ MGP_CASTEiJ_G0033721
 protein coding gene Chr9:43178878-43228502 (-)
CBA/J MGP_CBAJ_G0034371
 protein coding gene Chr9:46107267-46158777 (-)
DBA/2J MGP_DBA2J_G0034530
 protein coding gene Chr9:41893596-41942479 (-)
FVB/NJ MGP_FVBNJ_G0034471
 protein coding gene Chr9:41153718-41204172 (-)
LP/J MGP_LPJ_G0034611
 protein coding gene Chr9:43506809-43557026 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034515
 protein coding gene Chr9:47941254-47991154 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035230
 protein coding gene Chr9:42780677-42830331 (-)
PWK/PhJ MGP_PWKPhJ_G0033426
 protein coding gene Chr9:41778233-41827321 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033262
 protein coding gene Chr9:43088154-43136882 (-)
WSB/EiJ MGP_WSBEiJ_G0033834
 protein coding gene Chr9:42807507-42859125 (-)



Homology
more
  • Human Ortholog
    PHLDB1, pleckstrin homology like domain family B member 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PHLDB1, pleckstrin homology like domain family B member 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LL5A
  • Links
    NCBI Gene ID: 23187
    neXtProt AC: NX_Q86UU1
    UniProt: Q86UU1

  • Chr Location
    11q23.3; chr11:118606296-118658038 (+)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 15903
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PHLDB1
  • Gene Tree
    Phldb1
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    94
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048537 Ensembl Gene Model | MGI Sequence Detail 48895 C57BL/6J ±  kb
transcript ENSMUST00000138356 Ensembl | MGI Sequence Detail 5600 Not Applicable  
polypeptide ENSMUSP00000120208 Ensembl | MGI Sequence Detail 1449 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 94
    cDNA 94

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
02/18/2020
MGI 6.14 		The Jackson Laboratory