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Slc6a20a Gene Detail
Summary
  • Symbol
    Slc6a20a
  • Name
    solute carrier family 6 (neurotransmitter transporter), member 20A
  • Synonyms
    A730081N20Rik, Xtrp3s1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143217
    NCBI Gene: 102680
Location & Maps
more
  • Sequence Map
    Chr9:123636122-123678885 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      42764 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SLC6A20, solute carrier family 6 (proline IMINO transporter), member 20
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SLC6A20, solute carrier family 6 (proline IMINO transporter), member 20
    Orthology source: HomoloGene
  • Synonyms
    SIT1, XT3, Xtrp3
  • Links
    NCBI Gene ID: 54716
    neXtProt AC: NX_Q9NP91

  • Chr Location
    3p21.3; chr3:45755449-45796561 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    2 with human SLC6A20 associations

Human Disease Mouse Models
       Hyperglycinuria   OMIM: 138500
Iminoglycinuria   OMIM: 242600
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036109 VEGA Gene Model | MGI Sequence Detail 42764 C57BL/6J ±  kb
transcript OTTMUST00000092800 VEGA | MGI Sequence Detail 2732 Not Applicable  
polypeptide OTTMUSP00000051356 VEGA | MGI Sequence Detail 592 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    407 from dbSNP Build 137
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000015187 sodium- and chloride-dependent transporter XTRP3
  • InterPro Domains
    IPR000175 Sodium:neurotransmitter symporter
    IPR002438 Sodium:neurotransmitter symporter, orphan
Molecular
Reagents
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  • All nucleic 17
    cDNA 15
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
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MGI:2443096
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory