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Plekho2 Gene Detail
Summary
  • Symbol
    Plekho2
  • Name
    pleckstrin homology domain containing, family O member 2
  • Synonyms
    Plekhq1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143132
    NCBI Gene: 102595
  • Alliance
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:65552698-65580040 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 35.38 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    124 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143132
protein coding gene Chr9:65552577-65580087 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034962
protein coding gene Chr9:65302407-65330845 (-)
A/J MGP_AJ_G0034942
protein coding gene Chr9:63094879-63120094 (-)
AKR/J MGP_AKRJ_G0034872
protein coding gene Chr9:64583767-64608809 (-)
BALB/cJ MGP_BALBcJ_G0034935
protein coding gene Chr9:62817261-62842421 (-)
C3H/HeJ MGP_C3HHeJ_G0034645
protein coding gene Chr9:65114668-65142691 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035454
protein coding gene Chr9:67080798-67114275 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032365
protein coding gene Chr9:62743032-62767941 (-)
CAST/EiJ MGP_CASTEiJ_G0033966
protein coding gene Chr9:65300275-65325915 (-)
CBA/J MGP_CBAJ_G0034616
protein coding gene Chr9:69423452-69453858 (-)
DBA/2J MGP_DBA2J_G0034775
protein coding gene Chr9:62863434-62889021 (-)
FVB/NJ MGP_FVBNJ_G0034717
protein coding gene Chr9:62188444-62213756 (-)
LP/J MGP_LPJ_G0034858
protein coding gene Chr9:65569620-65597097 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034759
protein coding gene Chr9:70644953-70672453 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035476
protein coding gene Chr9:64691442-64718014 (-)
PWK/PhJ MGP_PWKPhJ_G0033670
protein coding gene Chr9:63068634-63093413 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033504
protein coding gene Chr9:64974920-65003499 (-)
WSB/EiJ MGP_WSBEiJ_G0034079
protein coding gene Chr9:64594770-64622818 (-)



Homology
more
  • Human Ortholog
    PLEKHO2, pleckstrin homology domain containing O2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PLEKHO2, pleckstrin homology domain containing O2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PLEKHQ1, PP1628, pp9099
  • Links
    NCBI Gene ID: 80301
    neXtProt AC: NX_Q8TD55
    UniProt: Q8TD55

  • Chr Location
    15q22.31; chr15:64841883-64868002 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050721 Ensembl Gene Model | MGI Sequence Detail 27343 C57BL/6J ±  kb
transcript ENSMUST00000068944 Ensembl | MGI Sequence Detail 3273 Not Applicable  
polypeptide ENSMUSP00000063677 Ensembl | MGI Sequence Detail 495 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 39
    cDNA 39

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Phenotypes 6
  • Earliest
    J:91812 Stryke D, et al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 2003 Jan 1;31(1):278-81
  • Latest
    J:270531 Zhang P, et al., PLEKHO2 is essential for M-CSF-dependent macrophage survival. Cell Signal. 2017 Sep;37:115-122

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory