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Ano10
Gene Detail
Symbol

Name
ID
Ano10
anoctamin 10
MGI:2143103
Synonyms
Tmem16k
Feature Type
protein coding gene
Genetic Map
Chromosome 9
72.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr9:122175879-122294374 bp, - strand
From Ensembl annotation of GRCm38

  118496 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14314  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ano10

Human
homologs
Human Homolog ANO10, anoctamin 10
NCBI Gene ID 55129
neXtProt AC  NX_Q9NW15
Human Synonyms  SCAR10, TMEM16K
Human Chr (Location)  3p22.1; chr3:43366326-43622068 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human ANO10
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ano10 interacts with 105 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cation transmembrane transport, cation transport, ...
Component integral component of membrane, intracellular, ...
Function calcium activated cation channel activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (71)    Tissues (67)    Images (19)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 71
cDNA source data(42)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(42) cDNA(42)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000037949 (Evidence)
Entrez Gene102566 (Evidence)
UniGene87676
DFCITC1576166, TC1596557, TC1636071, TC1624498, TC1615969
DoTSDT.101378776, DT.94273538, DT.101737266, DT.91565207, DT.91431994, DT.488544, DT.91353356
NIA Mouse Gene IndexU031459
Consensus CDS ProjectCCDS23645.1
International Mouse Knockout Project StatusAno10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037949 Ensembl Gene Model | MGI Sequence Detail 118496 C57BL/6J ±  kb
transcript ENSMUST00000042546 Ensembl | MGI Sequence Detail 2599 Not Applicable 
polypeptide ENSMUSP00000045214 Ensembl | MGI Sequence Detail 659 Not Applicable 

For the selected sequences
All sequences(62) RefSeq(16) UniProt(1)
Polymorphisms
SNPs within 2kb(508 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007632 Anoctamin/TMEM 16
Protein Ontology PR:000004056 anoctamin-10
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:198369 Suzuki J, et al., Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members. J Biol Chem. 2013 May 10;288(19):13305-16
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory