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Edc3 Gene Detail
Summary
  • Symbol
    Edc3
  • Name
    enhancer of mRNA decapping 3
  • Synonyms
    Lsm16, Yjdc
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142951
    NCBI Gene: 353190
  • Gene Overview
    MyGene.info: EDC3
Location & Maps
more
  • Sequence Map
    Chr9:57708540-57752499 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      43960 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 31.37 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    EDC3, enhancer of mRNA decapping 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EDC3, enhancer of mRNA decapping 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    hYjeF_N2-15q23, LSM16, MRT50, YJDC, YJEFN2
  • Links
    NCBI Gene ID: 80153
    neXtProt AC: NX_Q96F86
    UniProt: Q96F86

  • Chr Location
    15q24.1; chr15:74630558-74696045 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11827
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: EDC3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033365 VEGA Gene Model | MGI Sequence Detail 43960 C57BL/6J ±  kb
transcript OTTMUST00000083746 VEGA | MGI Sequence Detail 5708 Not Applicable  
polypeptide OTTMUSP00000045038 VEGA | MGI Sequence Detail 508 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    72 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 4
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
  • Latest
    J:239655 Zhou Z, et al., RNA Binding Protein Nanos2 Organizes Post-transcriptional Buffering System to Retain Primitive State of Mouse Spermatogonial Stem Cells. Dev Cell. 2015 Jul 06;34(1):96-107

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/15/2017
MGI 6.10
The Jackson Laboratory