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Cog8 Gene Detail
Summary
  • Symbol
    Cog8
  • Name
    component of oligomeric golgi complex 8
  • Synonyms
    C87832
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142885
    NCBI Gene: 97484
  • Gene Overview
    MyGene.info: COG8
Location & Maps
more
  • Sequence Map
    Chr8:107046289-107056689 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10401 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 53.55 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    COG8, component of oligomeric golgi complex 8
  • Vertebrate Orthologs
    9
  • Human Ortholog
    COG8, component of oligomeric golgi complex 8
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CDG2H, DOR1
  • Links
    NCBI Gene ID: 84342
    neXtProt AC: NX_Q96MW5

  • Chr Location
    16q22.1; chr16:69328621-69339623 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human COG8 associations

Human Disease Mouse Models
       Congenital Disorder of Glycosylation, Type Iih; CDG2H   OMIM: 611182
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    12
  • Gene trapped
    10
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022389 VEGA Gene Model | MGI Sequence Detail 10401 C57BL/6J ±  kb
transcript OTTMUST00000053497 VEGA | MGI Sequence Detail 4476 Not Applicable  
polypeptide OTTMUSP00000025437 VEGA | MGI Sequence Detail 640 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    47 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000005691 conserved oligomeric Golgi complex subunit 8
  • InterPro Domains
    IPR007255 Conserved oligomeric Golgi complex subunit 8
    IPR016632 Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae
    IPR016159 Cullin repeat-like-containing domain
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142836
References
more
  • Summaries
    All 31
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory