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Cog8
Gene Detail
Symbol

Name
ID
Cog8
component of oligomeric golgi complex 8
MGI:2142885
Synonyms
C87832
Feature Type
protein coding gene
Genetic Map
Chromosome 8
53.55 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:107046289-107056689 bp, - strand
From VEGA annotation of GRCm38

  10401 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:13018  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: COG8
Protein SuperFamily: conserved oligomeric Golgi complex, component 8
Gene Tree: Cog8

Human
homologs
COG8, component of oligomeric golgi complex 8
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 84342
neXtProt AC: NX_Q96MW5

Human Synonyms: CDG2H, DOR1

Human Chr (Location): 16q22.1; chr16:69328621-69339623 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human COG8

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(10) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cog8 interacts with 262 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process protein transport, transport
Component Golgi apparatus, Golgi transport complex, ...
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cog8    NEW 
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000022389 (Evidence)
Ensembl Gene Model ENSMUSG00000031916 (Evidence)
Entrez Gene 97484 (Evidence)
Consensus CDS Project CCDS22643.1
International Mouse Phenotyping Consortium Status Cog8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022389 VEGA Gene Model | MGI Sequence Detail 10401 C57BL/6J ±  kb
transcript OTTMUST00000053497 VEGA | MGI Sequence Detail 4476 Not Applicable 
polypeptide OTTMUSP00000025437 VEGA | MGI Sequence Detail 640 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(2) UniProt(4)
Polymorphisms
SNPs within 2kb(47 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007255 Conserved oligomeric Golgi complex subunit 8
InterPro IPR016632 Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae
InterPro IPR016159 Cullin repeat-like-containing domain
Protein Ontology PR:000005691 conserved oligomeric Golgi complex subunit 8
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)
Other
accession IDs
MGI:2142836

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory