About   Help   FAQ
Nek5 Gene Detail
Summary
  • Symbol
    Nek5
  • Name
    NIMA (never in mitosis gene a)-related expressed kinase 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142824
    NCBI Gene: 330721
Location & Maps
more
  • Sequence Map
    Chr8:22073616-22125053 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      51438 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 10.95 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    NEK5, NIMA related kinase 5
  • Vertebrate Orthologs
    8
  • Human Ortholog
    NEK5, NIMA related kinase 5
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 341676
    neXtProt AC: NX_Q6P3R8

  • Chr Location
    13q14.3; chr13:52036411-52130366 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Chemically induced (ENU)
    1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000060880 VEGA Gene Model | MGI Sequence Detail 51438 C57BL/6J ±  kb
transcript OTTMUST00000148788 VEGA | MGI Sequence Detail 2253 Not Applicable  
polypeptide OTTMUSP00000077294 VEGA | MGI Sequence Detail 627 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    47 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:84167 Forrest AR, et al., Exploration of the cell-cycle genes found within the RIKEN FANTOM2 data set. Genome Res. 2003 Jun;13(6B):1366-75
  • Latest
    J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/22/2016
MGI 6.06
The Jackson Laboratory