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Cog4 Gene Detail
Summary
  • Symbol
    Cog4
  • Name
    component of oligomeric golgi complex 4
  • Synonyms
    D8Ertd515e
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142808
    NCBI Gene: 102339
  • Gene Overview
    MyGene.info: COG4
Location & Maps
more
  • Sequence Map
    Chr8:110846600-110882227 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      35628 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    COG4, component of oligomeric golgi complex 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    COG4, component of oligomeric golgi complex 4
    Orthology source: HomoloGene
  • Synonyms
    CDG2J, COD1
  • Links
    NCBI Gene ID: 25839
    neXtProt AC: NX_Q9H9E3

  • Chr Location
    16q22.1; chr16:70480569-70523554 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 7155
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: COG4
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human COG4 associations

Human Disease Mouse Models
       Congenital Disorder of Glycosylation, Type Iij; CDG2J   OMIM: 613489
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037836 VEGA Gene Model | MGI Sequence Detail 35628 C57BL/6J ±  kb
transcript OTTMUST00000097598 VEGA | MGI Sequence Detail 2737 Not Applicable  
polypeptide OTTMUSP00000054747 VEGA | MGI Sequence Detail 785 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    166 from dbSNP Build 142
Protein
Information
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  • UniProt
    9 Sequences
  • Protein Ontology
    PR:000005687 conserved oligomeric Golgi complex subunit 4
  • InterPro Domains
    IPR013167 Conserved oligomeric Golgi complex, subunit 4
    IPR007528 RINT-1/Tip20
Molecular
Reagents
less
  • All nucleic 129
    cDNA 128
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1261770
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory