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Alg11
Gene Detail
 Symbol
Name
ID
Alg11
asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)
MGI:2142632
Feature Type protein coding gene
Genetic Map
Chromosome 8
10.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:22060721-22071627 bp, + strand
From VEGA annotation of GRCm38

  10907 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68893  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Alg11

Human
homologs
Human Homolog ALG11, ALG11, alpha-1,2-mannosyltransferase
NCBI Gene ID 440138
neXtProt AC  NX_Q2TAA5
Human Synonyms  CDG1P, GT8
Human Chr (Location)  13q14.2; chr13:52012387-52029648 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ALG11
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(9) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Alg11 interacts with 382 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process biosynthetic process
Component endoplasmic reticulum, integral component of membrane, ...
Function GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity, transferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000020828 (Evidence)
Ensembl Gene ModelENSMUSG00000063362 (Evidence)
Entrez Gene207958 (Evidence)
DFCITC1588158, TC1608798, TC1647756
DoTSDT.484488, DT.55266439, DT.99853820
NIA Mouse Gene IndexU042890
EC2.4.1.131
Consensus CDS ProjectCCDS40292.1, CCDS57613.1
International Mouse Knockout Project StatusAlg11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020828 VEGA Gene Model | MGI Sequence Detail 10907 C57BL/6J ±  kb
transcript OTTMUST00000049243 VEGA | MGI Sequence Detail 4960 Not Applicable 
polypeptide OTTMUSP00000022780 VEGA | MGI Sequence Detail 492 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(7) UniProt(2)
Polymorphisms SNPs within 2kb(1 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001296 Glycosyl transferase, family 1
Protein Ontology PR:000003939 GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
References (Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)
Other
accession IDs
MGI:2142790

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory