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Alg11 Gene Detail
Summary
  • Symbol
    Alg11
  • Name
    asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142632
    NCBI Gene: 207958
  • Gene Overview
    MyGene.info: ALG11
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:22060721-22071627 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 10.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142632
protein coding gene Chr8:22060721-22071627 (.)
129S1/SvImJ MGP_129S1SvImJ_G0033443
protein coding gene Chr8:19901233-19912137 (+)
A/J MGP_AJ_G0033423
protein coding gene Chr8:19253815-19264981 (+)
AKR/J MGP_AKRJ_G0033348
protein coding gene Chr8:19881293-19892242 (+)
BALB/cJ MGP_BALBcJ_G0033419
protein coding gene Chr8:19374837-19385742 (+)
C3H/HeJ MGP_C3HHeJ_G0033133
protein coding gene Chr8:20074984-20085885 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033935
protein coding gene Chr8:20751592-20762396 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030892
protein coding gene Chr8:16592704-16603509 (+)
CAST/EiJ MGP_CASTEiJ_G0032459
protein coding gene Chr8:19500672-19511599 (+)
CBA/J MGP_CBAJ_G0033108
protein coding gene Chr8:21578530-21589471 (+)
DBA/2J MGP_DBA2J_G0033263
protein coding gene Chr8:19224800-19235696 (+)
FVB/NJ MGP_FVBNJ_G0033207
protein coding gene Chr8:19020495-19031398 (+)
LP/J MGP_LPJ_G0033352
protein coding gene Chr8:19903099-19914014 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033250
protein coding gene Chr8:21174163-21185065 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033954
protein coding gene Chr8:19780383-19791012 (+)
PWK/PhJ MGP_PWKPhJ_G0032171
protein coding gene Chr8:18813923-18825306 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032004
protein coding gene Chr8:19170920-19181814 (+)
WSB/EiJ MGP_WSBEiJ_G0032575
protein coding gene Chr8:19976432-19987334 (+)



Homology
more
  • Human Ortholog
    ALG11, ALG11, alpha-1,2-mannosyltransferase
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ALG11, ALG11, alpha-1,2-mannosyltransferase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CDG1P, GT8
  • Links
    NCBI Gene ID: 440138
    neXtProt AC: NX_Q2TAA5
    UniProt: Q2TAA5

  • Chr Location
    13q14.3; chr13:52012387-52029648 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ALG11 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 207958 NCBI Gene Model | MGI Sequence Detail 10907 C57BL/6J ±  kb
transcript NR_040650 RefSeq | MGI Sequence Detail 4974 C57BL/6  
polypeptide Q3TZM9 UniProt | EBI | MGI Sequence Detail 492 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142790
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory