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Snx25 Gene Detail
Summary
  • Symbol
    Snx25
  • Name
    sorting nexin 25
  • Synonyms
    LOC382008, SBBI31
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142610
    NCBI Gene: 102141
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:46033261-46152159 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 26.03 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    595 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142610
protein coding gene Chr8:46033261-46152206 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033584
protein coding gene Chr8:45121926-45244563 (-)
A/J MGP_AJ_G0033566
protein coding gene Chr8:43370838-43486276 (-)
AKR/J MGP_AKRJ_G0033491
protein coding gene Chr8:44645374-44769797 (-)
BALB/cJ MGP_BALBcJ_G0033563
protein coding gene Chr8:43555853-43672554 (-)
C3H/HeJ MGP_C3HHeJ_G0033272
protein coding gene Chr8:45186331-45306397 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034079
protein coding gene Chr8:46828532-46950793 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031028
protein coding gene Chr8:39641914-39758674 (-)
CAST/EiJ MGP_CASTEiJ_G0032598
protein coding gene Chr8:44615276-44743478 (-)
CBA/J MGP_CBAJ_G0033251
protein coding gene Chr8:48728252-48849098 (-)
DBA/2J MGP_DBA2J_G0033404
protein coding gene Chr8:43182565-43300391 (-)
FVB/NJ MGP_FVBNJ_G0033345
protein coding gene Chr8:42677234-42793087 (-)
LP/J MGP_LPJ_G0033492
protein coding gene Chr8:45126111-45249244 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033390
protein coding gene Chr8:48792232-48919320 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034097
protein coding gene Chr8:44811200-44932364 (-)
PWK/PhJ MGP_PWKPhJ_G0032306
protein coding gene Chr8:42707951-42825060 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032142
protein coding gene Chr8:43964069-44088104 (-)
WSB/EiJ MGP_WSBEiJ_G0032714
protein coding gene Chr8:45067461-45188575 (-)



Homology
more
  • Human Ortholog
    SNX25, sorting nexin 25
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SNX25, sorting nexin 25
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MSTP043, SBBI31
  • Links
    NCBI Gene ID: 83891
    neXtProt AC: NX_Q9H3E2
    UniProt: Q9H3E2

  • Chr Location
    4q35.1; chr4:185204237-185363971 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038291 Ensembl Gene Model | MGI Sequence Detail 118899 C57BL/6J ±  kb
transcript ENSMUST00000110378 Ensembl | MGI Sequence Detail 3445 Not Applicable  
polypeptide ENSMUSP00000106007 Ensembl | MGI Sequence Detail 986 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 37
    cDNA 37

    Microarray probesets 3
Other
Accession IDs
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MGI:2685019, MGI:2686545
References
more
  • Summaries
    All 28
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
  • Latest
    J:205663 Hao X, et al., SNX25 regulates TGF-beta signaling by enhancing the receptor degradation. Cell Signal. 2011 May;23(5):935-46

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory