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Slc7a6
Gene Detail
 Symbol
Name
ID
Slc7a6
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6
MGI:2142598
Synonyms LAT-2
Feature Type protein coding gene
Genetic Map
Chromosome 8
53.10 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:106168875-106198704 bp, + strand
From NCBI annotation of GRCm38

  29830 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:62496  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: amino acid transporter
Gene Tree: Slc7a6

Human
homologs
Human Homolog SLC7A6, solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
NCBI Gene ID 9057
neXtProt AC  NX_Q92536
Human Synonyms  LAT-2, LAT3, y+LAT-2
Human Chr (Location)  16q22.1; chr16:68264516-68301823 (+)  GRCh38
Alleles
and
phenotypes
All alleles(23) : Targeted(3) Gene trapped(20)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process amino acid transmembrane transport, amino acid transport, ...
Component integral component of membrane, membrane, ...
Function amino acid transmembrane transporter activity, antiporter activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (12)    Tissues (9)    Images (2)
Theiler Stages: 23, 28
Assay TypeResults
RNA in situ 2
RT-PCR 10
cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(17) cDNA(15) Primer pair(2)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000031904 (Evidence)
Entrez Gene330836 (Evidence)
DFCITC1572301, TC1589178, TC1611230, TC1615495, TC1629052, TC1631419, TC1692382
DoTSDT.101168909, DT.101191936, DT.101364302, DT.101398574, DT.101738593, DT.110907977, DT.110907980, DT.94126812, DT.94163490, DT.99862474
NIA Mouse Gene IndexU009769
Consensus CDS ProjectCCDS22631.1
International Mouse Knockout Project StatusSlc7a6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 330836 NCBI Gene Model | MGI Sequence Detail 29830 C57BL/6J ±  kb
transcript NM_178798 RefSeq | MGI Sequence Detail 3730 C57BL/6 
polypeptide Q8BGK6 UniProt | EBI | MGI Sequence Detail 515 Not Applicable 

For the selected sequences
All sequences(73) RefSeq(10) UniProt(1)
Polymorphisms SNPs within 2kb(102 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002293 Amino acid/polyamine transporter I
Protein Ontology PR:000015202 Y+L amino acid transporter 2
Graphical View of Protein Domain Structure
References (Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory