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Slc7a6
Gene Detail
Symbol

Name
ID
Slc7a6
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6
MGI:2142598
Synonyms
LAT-2
Feature Type
protein coding gene
Genetic Map
Chromosome 8
53.10 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:106168875-106198704 bp, + strand
From Ensembl annotation of GRCm38

  29830 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:62496  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SLC7A6
Protein SuperFamily: amino acid transporter
Gene Tree: Slc7a6

Human
homologs
SLC7A6, solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9057
neXtProt AC: NX_Q92536

Human Synonyms: LAT-2, LAT3, y+LAT-2

Human Chr (Location): 16q22.1; chr16:68263830-68301823 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(23) : Gene trapped(20) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Slc7a6 interacts with 239 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (12)    Tissues (10)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 2
RT-PCR 10
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc7a6    NEW 
Molecular
reagents
All nucleic(17) cDNA(15) Primer pair(2)
Microarray probesets(6)
Other database
links
Ensembl Gene Model ENSMUSG00000031904 (Evidence)
Entrez Gene 330836 (Evidence)
DFCI TC1629052, TC1589178, TC1572301, TC1615495, TC1611230, TC1631419, TC1692382
DoTS DT.101398574, DT.101364302, DT.101191936, DT.101168909, DT.110907980, DT.110907977, DT.101738593, DT.94126812, DT.99862474, DT.94163490
NIA Mouse Gene Index U009769
Consensus CDS Project CCDS22631.1
International Mouse Phenotyping Consortium Status Slc7a6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031904 Ensembl Gene Model | MGI Sequence Detail 29830 C57BL/6J ±  kb
transcript ENSMUST00000034378 Ensembl | MGI Sequence Detail 3730 Not Applicable 
polypeptide ENSMUSP00000034378 Ensembl | MGI Sequence Detail 515 Not Applicable 

For the selected sequences
All sequences(74) RefSeq(10) UniProt(1)
Polymorphisms
SNPs within 2kb(102 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002293 Amino acid/polyamine transporter I
Protein Ontology PR:000015202 Y+L amino acid transporter 2
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory