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Plekhg4
Gene Detail
Symbol

Name
ID
Plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
MGI:2142544
Synonyms
4931414L13Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 8
53.04 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:105373274-105382862 bp, + strand
From VEGA annotation of GRCm38

  9589 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18516  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Plekhg4

Human
homologs
Human Homolog PLEKHG4, pleckstrin homology domain containing, family G (with RhoGef domain) member 4
NCBI Gene ID 25894
neXtProt AC  NX_Q58EX7
Human Synonyms  ARHGEF44, PRTPHN1, SCA4
Human Chr (Location)  16q22.1; chr16:67277510-67289500 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Plekhg4 interacts with 332 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process biological_process
Component cellular_component
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (10)    Tissues (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 10
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(7) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000033516 (Evidence)
Ensembl Gene ModelENSMUSG00000014782 (Evidence)
Entrez Gene102075 (Evidence)
UniGene32034
DFCITC1587830, TC1600903
DoTSDT.101718599, DT.110868800, DT.40156691
NIA Mouse Gene IndexU009746
Consensus CDS ProjectCCDS40458.1
International Mouse Knockout Project StatusPlekhg4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033516 VEGA Gene Model | MGI Sequence Detail 9589 C57BL/6J ±  kb
transcript OTTMUST00000084322 VEGA | MGI Sequence Detail 4167 Not Applicable 
polypeptide OTTMUSP00000045427 VEGA | MGI Sequence Detail 1181 Not Applicable 

For the selected sequences
All sequences(55) RefSeq(16) UniProt(5)
Polymorphisms
SNPs within 2kb(26 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000219 Dbl homology (DH) domain
InterPro IPR001849 Pleckstrin homology domain
InterPro IPR011993 Pleckstrin homology-like domain
Protein Ontology PR:000012861 puratrophin-1
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory