About   Help   FAQ
Plekhg4 Gene Detail
Summary
  • Symbol
    Plekhg4
  • Name
    pleckstrin homology domain containing, family G (with RhoGef domain) member 4
  • Synonyms
    4931414L13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142544
    NCBI Gene: 102075
  • Gene Overview
    MyGene.info: PLEKHG4
Location & Maps
more
  • Sequence Map
    Chr8:105373274-105382862 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9589 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    PLEKHG4, pleckstrin homology and RhoGEF domain containing G4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PLEKHG4, pleckstrin homology and RhoGEF domain containing G4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ARHGEF44, PRTPHN1, SCA4
  • Links
    NCBI Gene ID: 25894
    neXtProt AC: NX_Q58EX7

  • Chr Location
    16q22.1; chr16:67277820-67289500 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033516 VEGA Gene Model | MGI Sequence Detail 9589 C57BL/6J ±  kb
transcript OTTMUST00000084322 VEGA | MGI Sequence Detail 4167 Not Applicable  
polypeptide OTTMUSP00000045427 VEGA | MGI Sequence Detail 1181 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    29 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:219050 Gupta M, et al., Plekhg4 is a novel Dbl family guanine nucleotide exchange factor protein for rho family GTPases. J Biol Chem. 2013 May 17;288(20):14522-30

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/17/2016
MGI 6.03
The Jackson Laboratory