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Exoc8 Gene Detail
Summary
  • Symbol
    Exoc8
  • Name
    exocyst complex component 8
  • Synonyms
    EXO84, Exo84p, SEC84
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142527
    NCBI Gene: 102058
  • Gene Overview
    MyGene.info: EXOC8
Location & Maps
more
  • Sequence Map
    Chr8:124890300-124897705 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7406 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    EXOC8, exocyst complex component 8
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EXOC8, exocyst complex component 8
    Orthology source: HomoloGene
  • Synonyms
    EXO84, Exo84p, SEC84
  • Links
    NCBI Gene ID: 149371
    neXtProt AC: NX_Q8IYI6

  • Chr Location
    1q42.2; chr1:231332731-231337872 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 44545
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: EXOC8
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074030 Ensembl Gene Model | MGI Sequence Detail 7406 C57BL/6J ±  kb
transcript ENSMUST00000098312 Ensembl | MGI Sequence Detail 7406 Not Applicable  
polypeptide ENSMUSP00000095915 Ensembl | MGI Sequence Detail 716 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    78 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000007256 exocyst complex component 8
  • InterPro Domains
    IPR016159 Cullin repeat-like-containing domain
    IPR032403 Exocyst component Exo84, C-terminal
    IPR011993 PH domain-like
    IPR001849 Pleckstrin homology domain
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 4
Other
Accession IDs
less
MGI:2142891
References
more
  • Summaries
    All 27
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory